Chimeric Antigen Receptor (CAR) T cell therapy has recently begun to be used for solid
tumors such as glioblastoma multiforme. Many children with pediatric malignant brain …

Hepatocyte growth factor (HGF) ligand and its receptor tyrosine kinase (RTK) mesenchymal-
epithelial transition factor (MET) are important regulators of cellular processes such as …

Biallelic inactivation of SMARCB1, encoding a member of the SWI/SNF chromatin
remodeling complex, is the hallmark genetic aberration of atypical teratoid rhabdoid tumors …

Together, medulloblastoma (MB) and atypical teratoid/rhabdoid tumors (AT/RT) represent
two of the most prevalent pediatric brain malignancies. Current treatment involves radiation …

Introduction Atypical teratoid/rhabdoid tumor (AT/RT) is a highly aggressive embryonal CNS
neoplasm, characterized by inactivation of SMARCB1 (INI1) or rarely of SMARCA4 (BRG1) …

Previous results revealed that arsenic trioxide might be used as promising therapeutic agent
for the treatment of some solid tumours as atypical teratoid rhabdoid tumours (ATRT) …

Embryonal tumors of the central nervous system (CNS) are highly malignant undifferentiated
or poorly differentiated tumors of neuroepithelial origin and have been defined as a category …

Purpose: Atypical teratoid/rhabdoid tumors (AT/RT) and central nervous system primitive
neuroectodermal tumors (CNS-PNET) are pediatric brain tumors with poor survival and life …

Abstract Atypical Teratoid Rhabdoid Tumor (AT/RT) is a rare pediatric central nervous
system cancer often characterized by deletion or mutation of SMARCB1, a tumor suppressor …

It is still unclear what drives progression of childhood tumors. During Drosophila larval
development, asymmetrically-dividing neural stem cells, called neuroblasts, progress …