The cellular lives of Wolbachia

J Porter, W Sullivan - Nature Reviews Microbiology, 2023 - nature.com
Wolbachia are successful Gram-negative bacterial endosymbionts, globally infecting a large
fraction of arthropod species and filarial nematodes. Efficient vertical transmission, the …

Wolbachia-Virus interactions and arbovirus control through population replacement in mosquitoes

TH Ant, MV Mancini, CJ McNamara… - … and Global Health, 2023 - Taylor & Francis
Following transfer into the primary arbovirus vector Aedes aegypti, several strains of the
intracellular bacterium Wolbachia have been shown to inhibit the transmission of dengue …

Two-By-One model of cytoplasmic incompatibility: Synthetic recapitulation by transgenic expression of cifA and cifB in Drosophila

JD Shropshire, SR Bordenstein - PLoS genetics, 2019 - journals.plos.org
Wolbachia are maternally inherited bacteria that infect arthropod species worldwide and are
deployed in vector control to curb arboviral spread using cytoplasmic incompatibility (CI). CI …

Engineered resistance to Zika virus in transgenic Aedes aegypti expressing a polycistronic cluster of synthetic small RNAs

A Buchman, S Gamez, M Li… - Proceedings of the …, 2019 - National Acad Sciences
Recent Zika virus (ZIKV) outbreaks have highlighted the necessity for development of novel
vector control strategies to combat arboviral transmission, including genetic versions of the …

[HTML][HTML] Dual Insect specific virus infection limits Arbovirus replication in Aedes mosquito cells

MJ Schultz, HM Frydman, JH Connor - Virology, 2018 - Elsevier
Aedes mosquitoes are vectors for many pathogenic viruses. Cell culture systems facilitate
the investigation of virus growth in the mosquito vector. We found Zika virus (ZIKV) growth to …

Zika virus infection: an update

P Ferraris, H Yssel, D Missé - Microbes and infection, 2019 - Elsevier
Since the ZIKV outbreak in Brazil in 2015, the scientific community has joined efforts to
gather more information on the epidemiology, clinical features and pathogenicity of the virus …

Conflict in the Intracellular Lives of Endosymbionts and Viruses: A Mechanistic Look at Wolbachia-Mediated Pathogen-blocking

ARI Lindsey, T Bhattacharya, ILG Newton, RW Hardy - Viruses, 2018 - mdpi.com
At the forefront of vector control efforts are strategies that leverage host-microbe associations
to reduce vectorial capacity. The most promising of these efforts employs Wolbachia, a …

Uncovering the Worldwide Diversity and Evolution of the Virome of the Mosquitoes Aedes aegypti and Aedes albopictus

R Parry, ME James, S Asgari - Microorganisms, 2021 - mdpi.com
Aedes aegypti, the yellow fever mosquito, and Aedes albopictus, the Asian tiger mosquito,
are the most significant vectors of dengue, Zika, and Chikungunya viruses globally. Studies …

Aedes anphevirus: an insect-specific virus distributed worldwide in Aedes aegypti mosquitoes that has complex interplays with Wolbachia and dengue virus infection …

R Parry, S Asgari - Journal of Virology, 2018 - Am Soc Microbiol
Insect-specific viruses (ISVs) of the yellow fever mosquito Aedes aegypti have been
demonstrated to modulate transmission of arboviruses such as dengue virus (DENV) and …

Hype or opportunity? Using microbial symbionts in novel strategies for insect pest control

AK Arora, AE Douglas - Journal of insect physiology, 2017 - Elsevier
All insects, including pest species, are colonized by microorganisms, variously located in the
gut and within insect tissues. Manipulation of these microbial partners can reduce the pest …