Despite the numerous uses of chitin and chitosan as new functional materials of high
potential in various fields, they are still behind several directly compressible excipients …

The objective of this work is to present a review of computational tools and models for
pharmaceutical processes, specifically those for the continuous manufacture of solid dosage …

The roller compaction process has gained heightened interest in the pharmaceutical
industry. In this review, common excipients and equipment used for dry granulation are …

Very limited work has been reported on comparing the performance of the roller compaction
process at different scales. The majority of the approaches highlighted in the literature …

Roller compaction is one stage in a dry granulation process to produce free flowing
granules. Its proper understanding is essential in optimising manufacturing efficiency and …

Disturbance propagation during continuous manufacturing processes can be predicted by
evaluating the residence time distribution (RTD) of the specific unit operations. In this work, a …

We derive a dynamic model for roller compaction process based on Johanson's rolling
theory, which is used to predict the stress and density profiles during the compaction and the …

What is the role of standardized methods for determining the impact of material properties in
pharmaceutical formulation and process development? In this Perspective article, we …

Enabling the paradigm of quality by design requires the ability to quantitatively correlate
material properties and process variables to measureable product performance attributes. In …

One of primary goals of the Quality by Design initiative in the pharmaceutical industry is to
reduce variation in the product quality through increased understanding and control of the …