Lower vertebrate and invertebrate models of Alzheimer's disease–A review

N Sharma, N Khurana, A Muthuraman - European journal of pharmacology, 2017 - Elsevier
Alzheimer's disease is a common neurodegenerative disorder which is characterized by the
presence of beta-amyloid protein and neurofibrillary tangles (NFTs) in the brain. Till now …

Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility

R Ramanagoudr-Bhojappa, B Carrington… - PLoS …, 2018 - journals.plos.org
Fanconi Anemia (FA) is a genomic instability syndrome resulting in aplastic anemia,
developmental abnormalities, and predisposition to hematological and other solid organ …

Assessing the spectrum of germline variation in Fanconi anemia genes among patients with head and neck carcinoma before age 50

SC Chandrasekharappa, SB Chinn, FX Donovan… - Cancer, 2017 - Wiley Online Library
BACKGROUND Patients with Fanconi anemia (FA) have an increased risk for head and
neck squamous cell carcinoma (HNSCC). The authors sought to determine the prevalence …

The FANCC–FANCE–FANCF complex is evolutionarily conserved and regulates meiotic recombination

DK Singh, RS Gamboa, AK Singh… - Nucleic Acids …, 2023 - academic.oup.com
At meiosis, programmed meiotic DNA double-strand breaks are repaired via homologous
recombination, resulting in crossovers (COs). From a large excess of DNA double-strand …

Shifting evolutionary sands: transcriptome characterization of the Aptostichus atomarius species complex

NL Garrison, MS Brewer, JE Bond - BMC Evolutionary Biology, 2020 - Springer
Background Mygalomorph spiders represent a diverse, yet understudied lineage for which
genomic level data has only recently become accessible through high-throughput genomic …

Clonal dominance in bone marrow failure syndromes

PHDL Prata - 2022 - theses.hal.science
Bone marrow failure syndromes (BMF) are a diverse group of rare diseases that manifest
chiefly with pancytopenia. The incapacity of the haematopoietic tissue to sustain …

[PDF][PDF] Clonal dominance in bone marrow failure syndromes

PH de Lima Prata - 2022 - theses.fr
Les insuffisances médullaires sont des maladies rares qui se manifestent principalement
par pancytopénie. L'incapacité du tissu hématopoïétique à maintenir l'hématopoïèse peut …

[图书][B] A molecular genetic investigation of FANCI as a new candidate ovarian cancer predisposing gene

C Fierheller - 2022 - search.proquest.com
Heterozygous carriers of loss-of-function (pathogenic) variants in BRCA1 or BRCA2 have an
estimated absolute risk of 13 to 58% for ovarian cancer, especially of high grade serous …

[HTML][HTML] Identification of key protein-coding genes in lung adenocarcinomas based on bioinformatic analysis

R Yao, X Chen, L Wang, Y Wang, S Chi… - Translational Cancer …, 2019 - ncbi.nlm.nih.gov
Background Lung cancer is one of the most common cancers and the primary cause of
cancer-related deaths in the world. The 5-year survival of lung cancer patients is lower than …

[PDF][PDF] NAR Breakthrough Article The FANCC–FANCE–FANCF complex is evolutionarily

DK Singh, RS Gamboa, AK Singh… - Nucleic Acids …, 2023 - mpipz.mpg.de
At meiosis, programmed meiotic DNA double-strand breaks are repaired via homologous
recombination, resulting in crossovers (COs). From a large excess of DNA double-strand …