[HTML][HTML] Cannabis and its secondary metabolites: their use as therapeutic drugs, toxicological aspects, and analytical determination

J Gonçalves, T Rosado, S Soares, AY Simão… - Medicines, 2019 - mdpi.com
Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …

[HTML][HTML] Impacts of medical and non-medical cannabis on the health of older adults: findings from a scoping review of the literature

D Wolfe, K Corace, C Butler, D Rice, B Skidmore… - PLoS …, 2023 - journals.plos.org
Background Cannabis legalization has enabled increased consumption in older adults. Age-
related mental, physical, and physiological changes may lead to differences in effects of …

[HTML][HTML] Potential and limits of cannabinoids in Alzheimer's disease therapy

G Abate, D Uberti, S Tambaro - Biology, 2021 - mdpi.com
Simple Summary This review was aimed at exploring the potentiality of drugging the
endocannabinoid system as a therapeutic option for Alzheimer's disease (AD). Recent …

[HTML][HTML] Therapeutic properties of multi-cannabinoid treatment strategies for Alzheimer's disease

M Coles, GZ Steiner-Lim, T Karl - Frontiers in Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterized by
declining cognition and behavioral impairment, and hallmarked by extracellular amyloid-β …

[HTML][HTML] Quality of life and a surveillant endocannabinoid system

RA de Melo Reis, AR Isaac, HR Freitas… - Frontiers in …, 2021 - frontiersin.org
The endocannabinoid system (ECS) is an important brain modulatory network. ECS
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …

Cannabinoids in neuroinflammatory disorders: Focusing on multiple sclerosis, Parkinsons, and Alzheimers diseases

B Abd‐Nikfarjam, A Dolati‐Somarin… - …, 2023 - Wiley Online Library
The medicinal properties of cannabis and cannabinoid‐derivative are entirely investigated
and known. In addition, the identification of psychotropic plant cannabinoids has led to more …

[HTML][HTML] A phase 2 randomised clinical trial assessing the tolerability of two different ratios of medicinal cannabis in patients with high grade gliomas

J Schloss, J Lacey, M Sughrue, C Teo - Frontiers in oncology, 2021 - frontiersin.org
Background Cannabis for cancer is very topical and, given the use of illicit cannabis
preparations used in this vulnerable population, research investigating standardised, quality …

Cannabis: a treasure trove or pandora's box?

K Solymosi, A Köfalvi - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …

[HTML][HTML] Phytocannabinoids and cannabis-based products as alternative pharmacotherapy in neurodegenerative diseases: From hypothesis to clinical practice

Y Paes-Colli, AFL Aguiar, AR Isaac… - Frontiers in cellular …, 2022 - frontiersin.org
Historically, Cannabis is one of the first plants to be domesticated and used in medicine,
though only in the last years the amount of Cannabis-based products or medicines has …

Cannabis dosing and administration for sleep: a systematic review

R Velzeboer, A Malas, P Boerkoel, K Cullen… - Sleep, 2022 - academic.oup.com
Study objectives As cannabis is increasingly used to treat sleep disorders, we performed a
systematic review to examine the effects of cannabis on sleep and to guide cannabis …