A little over 50 years ago, Sydney Brenner had the foresight to develop the nematode (round
worm) Caenorhabditis elegans as a genetic model for understanding questions of …

Salt stress is an ever-present threat to crop yields, especially in countries with irrigated
agriculture. Efforts to improve salt tolerance in crop plants are vital for sustainable crop …

The majority of agronomic traits are controlled by multiple genes that cause minor
phenotypic effects, making the identification of these genes difficult. Here we introduce …

Forward genetic screens in model organisms are vital for identifying novel genes essential
for developmental or disease processes. One drawback of these screens is the labor …

The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …

Whole genome sequencing (WGS) allows researchers to pinpoint genetic differences
between individuals and significantly shortcuts the costly and time-consuming part of …

Next‐generation genomic sequencing technologies have made it possible to directly map
mutations responsible for phenotypes of interest via direct sequencing. However, most …

Genomic resources for hundreds of species of evolutionary, agricultural, economic, and
medical importance are unavailable due to the expense of well-assembled genome …

Whole-genome sequencing (WGS) is becoming a fast and cost-effective method to pinpoint
molecular lesions in mutagenized genetic model systems, such as Caenorhabditis elegans …

Salinity is an ever-present major constraint and a major threat to legume crops, particularly
in areas with irrigated agriculture. Legumes demonstrate high sensitivity, especially during …