Photodynamic therapy for the treatment of glioblastoma

SW Cramer, CC Chen - Frontiers in Surgery, 2020 - frontiersin.org
Glioblastoma is the most common form of adult brain cancer and remains one of the
deadliest of human cancers. The current standard-of-care involves maximal tumor resection …

The use of photodynamic therapy in the treatment of brain tumors—A review of the literature

D Bartusik-Aebisher, A Żołyniak, E Barnaś… - Molecules, 2022 - mdpi.com
The treatment of neoplastic disease of the brain is still a challenge for modern medicine.
Therefore, advanced methodologies are needed that can rationally and successfully …

Systematic review of photodynamic therapy in gliomas

T Hsia, JL Small, A Yekula, SM Batool, AK Escobedo… - Cancers, 2023 - mdpi.com
Simple Summary Malignant gliomas are of the deadliest, most hard-to-treat cancers, given
their various characteristics of aggression and infiltration as well as the location of growth …

PAMAM dendrimer nanomolecules utilized as drug delivery systems for potential treatment of glioblastoma: a systematic review

M Fana, J Gallien, B Srinageshwar… - International journal …, 2020 - Taylor & Francis
Glioblastoma (GB) is a grade IV astrocytoma that maintains a poor prognosis with respect to
current treatment options. Despite major advancements in the fields of surgery and …

Electrotherapies for glioblastoma

EPW Jenkins, A Finch, M Gerigk, IF Triantis… - Advanced …, 2021 - Wiley Online Library
Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …

Research progress on nanoplatforms and nanotherapeutic strategies in treating glioma

L Qiao, H Yang, X Shao, Q Yin, XJ Fu… - Molecular …, 2022 - ACS Publications
Glioma is the most common and aggressive primary intracranial tumor within the central
nervous system. The blood–brain barrier (BBB) has been a great hurdle for an effective …

[HTML][HTML] Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling …

L Lu, G Chen, J Yang, Z Ma, Y Yang, Y Hu, Y Lu… - Biomedicine & …, 2019 - Elsevier
Mesenchymal stem cells (MSCs), with the capacity for self-renewal and differentiation into
multiple cell types, exhibit the property of homing towards tumor sites and …

Targeted and synergic glioblastoma treatment: multifunctional nanoparticles delivering verteporfin as adjuvant therapy for temozolomide chemotherapy

DS Pellosi, LB Paula, MT de Melo… - Molecular …, 2019 - ACS Publications
Despite advances in cancer therapies, glioblastoma multiforme treatment remains inefficient
due to the brain–blood barrier (BBB) inhibitory activity and to the low temozolomide (TMZ) …

Trojan horse monocyte-mediated delivery of conjugated polymer nanoparticles for improved photodynamic therapy of glioblastoma

LE Ibarra, L Beaugé, N Arias-Ramos, VA Rivarola… - …, 2020 - Taylor & Francis
Aim: To assess monocyte-based delivery of conjugated polymer nanoparticles (CPNs) for
improved photodynamic therapy (PDT) in glioblastoma (GBM). Materials & methods: Human …

Mechanisms of photodynamic therapy

D Sharma, S Singh, P Kumar, GK Jain… - Nanomaterials for …, 2023 - Elsevier
Photodynamic therapy (PDT) is an established photochemical treatment. PDT uses
photosensitizer (PSs) that are excited by light at a particular wavelength after being …