Background Unraveling the mechanisms that regulate gene expression is a major challenge
in biology. An important task in this challenge is to identify regulatory elements, especially …

The DNA motif discovery is a primary step in many systems for studying gene function. Motif
discovery plays a vital role in identification of Transcription Factor Binding Sites (TFBSs) that …

The DNA motif discovery (MD) problem is the main challenge of genome biology, and its
importance is directly proportional to increasing sequencing technologies. MD plays a vital …

Motivation: Identification of a transcription factor binding sites is an important aspect of the
analysis of genetic regulation. Many programs have been developed for the de novo …

Computational DNA motif discovery is important because it allows for speedy and cost
effective analysis of sequences enriched with DNA motifs, performs large scale comparative …

We propose an efficient method using multi-objective genetic algorithm (MOGAMOD) to
discover optimal motifs in sequential data. The main advantage of our approach is that a …

Computationally identifying transcription factor binding sites in the promoter regions of
genes is an important problem in computational biology and has been under intensive …

The conserved regions between genomic sequences extracted from the different species
give important information about the complex regulatory mechanisms of the transcription …

Motivation: Identification of transcription factor binding sites (TFBSs) plays an important role
in deciphering the mechanisms of gene regulation. Recently, GAME, a Genetic Algorithm …

Life may have begun in an RNA world, which is supported by increasing evidence of the
vital role that RNAs perform in biological systems. In the human genome, most genes …