Amyloid-β: a potential link between epilepsy and cognitive decline

M Romoli, A Sen, L Parnetti, P Calabresi… - Nature Reviews …, 2021 - nature.com
People with epilepsy—in particular, late-onset epilepsy of unknown aetiology—have an
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …

Systematic review of coexistent epileptic seizures and Alzheimer's disease: Incidence and prevalence

Y Xu, L Lavrencic, K Radford, A Booth… - Journal of the …, 2021 - Wiley Online Library
Abstract Background/Objectives Coexistent seizures add complexity to the burden of
Alzheimer's disease (AD). We aim to estimate the incidence and prevalence of coexistent …

Bi-directional association between epilepsy and dementia: The Framingham Heart Study

M Stefanidou, AS Beiser, JJ Himali, TJ Peng… - Neurology, 2020 - AAN Enterprises
Objective To assess the risk of incident epilepsy among participants with prevalent dementia
and the risk of incident dementia among participants with prevalent epilepsy in the …

Childhood trauma in patients with epileptic vs nonepileptic seizures

T Yang, C Roberts, T Winton‐Brown, M Lloyd… - …, 2023 - Wiley Online Library
Objective Childhood trauma has been implicated as a risk factor for the etiology of
psychogenic nonepileptic seizures (PNES). Relatively little attention has been paid to …

Ginsenoside Rg1 improved learning and memory ability and reduces neuronal apoptosis in epileptic rats through ERK/CREB/BDNF signal pathway

J Zhang, C Zhu, Y Jin, W Shen, Y Pan… - … and Biophysical Research …, 2023 - Elsevier
Objective This research was devoted to estimating the outcomes of ginsenoside Rg1 on
learning and memory ability and neuronal apoptosis in epileptic rats through …

Chronic pediatric diseases and risk for reading difficulties: a narrative review with recommendations

D Perazzo, R Moore, NA Kasparian, M Rodts… - Pediatric …, 2022 - nature.com
Literacy is a major social determinant of health, rooted in skills that develop during early
childhood. Children arriving at kindergarten unprepared to learn to read are more likely to …

[HTML][HTML] Cognitive disorders in epilepsy II: Clinical targets, indications and selection of test instruments

C Helmstaedter, Z Sadat-Hossieny, AM Kanner… - Seizure, 2020 - Elsevier
This is the second of two narrative reviews on cognitive disorders in epilepsy (companion
manuscript: Cognitive disorders in epilepsy I: Clinical experience, real-world evidence and …

[HTML][HTML] Dosage, time, and polytherapy dependent effects of different levetiracetam regimens on cognitive function

JD Perkins, MS Abdelmoneim, SS Wilkins, S Kamran… - Epilepsy & Behavior, 2023 - Elsevier
Objective Cognitive impairment is a potential drawback of antiseizure medications. This
study aimed to evaluate the impact of different levetiracetam drug regimens on cognitive …

Telmisartan, an Antagonist of Angiotensin II Receptors, Accentuates Voltage-Gated Na+ Currents and Hippocampal Neuronal Excitability

MC Lai, SN Wu, CW Huang - Frontiers in Neuroscience, 2020 - frontiersin.org
Telmisartan (TEL), a non-peptide blocker of the angiotensin II type 1 receptor, is a widely
used antihypertensive agent. Nevertheless, its neuronal ionic effects and how they …

Multidimensional psychopathological profile differences between patients with psychogenic nonepileptic seizures and epileptic seizure disorders

M Lloyd, TT Winton-Brown, A Hew, G Rayner… - Epilepsy & Behavior, 2022 - Elsevier
Objective Early differential diagnosis of psychogenic nonepileptic seizures (PNES) and
epileptic seizures (ES) remains difficult. Self-reported psychopathology is often elevated in …