Microbial rhodopsins: diversity, mechanisms, and optogenetic applications

EG Govorunova, OA Sineshchekov, H Li… - Annual review of …, 2017 - annualreviews.org
Microbial rhodopsins are a family of photoactive retinylidene proteins widespread
throughout the microbial world. They are notable for their diversity of function, using …

[HTML][HTML] Rhodopsins: an excitingly versatile protein species for research, development and creative engineering

WJ de Grip, S Ganapathy - Frontiers in Chemistry, 2022 - frontiersin.org
The first member and eponym of the rhodopsin family was identified in the 1930s as the
visual pigment of the rod photoreceptor cell in the animal retina. It was found to be a …

[HTML][HTML] Crystal structure of the natural anion-conducting channelrhodopsin GtACR1

YS Kim, HE Kato, K Yamashita, S Ito, K Inoue… - Nature, 2018 - nature.com
The naturally occurring channelrhodopsin variant anion channelrhodopsin-1 (ACR1),
discovered in the cryptophyte algae Guillardia theta, exhibits large light-gated anion …

Antimicrobial and antioxidant AIE chitosan-based films incorporating a Pickering emulsion of lemon myrtle (Backhousia citriodora) essential oil

L Liu, S Swift, C Tollemache, J Perera, PA Kilmartin - Food Hydrocolloids, 2022 - Elsevier
Films based on chitosan (CS) and Lemon Myrtle (Backhousia citriodora) essential oil (LEO)
were prepared that exhibited novel dose-dependent fluorescent patterns owing to …

[HTML][HTML] The expanding family of natural anion channelrhodopsins reveals large variations in kinetics, conductance, and spectral sensitivity

EG Govorunova, OA Sineshchekov, EM Rodarte… - Scientific reports, 2017 - nature.com
Natural anion channelrhodopsins (ACRs) discovered in the cryptophyte alga Guillardia theta
generate large hyperpolarizing currents at membrane potentials above the Nernst …

[HTML][HTML] MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins

J Oppermann, P Fischer, A Silapetere, B Liepe… - Nature …, 2019 - nature.com
Channelrhodopsins (ChRs) are algal light-gated ion channels widely used as optogenetic
tools for manipulating neuronal activity. ChRs desensitize under continuous bright-light …

[HTML][HTML] Raman scattering: from structural biology to medical applications

AV Vlasov, NL Maliar, SV Bazhenov, EI Nikelshparg… - Crystals, 2020 - mdpi.com
This is a review of relevant Raman spectroscopy (RS) techniques and their use in structural
biology, biophysics, cells, and tissues imaging towards development of various medical …

[HTML][HTML] Crystal structure of a natural light-gated anion channelrhodopsin

H Li, CY Huang, EG Govorunova, CT Schafer… - Elife, 2019 - elifesciences.org
The anion channelrhodopsin Gt ACR1 from the alga Guillardia theta is a potent neuron-
inhibiting optogenetics tool. Presented here, its X-ray structure at 2.9 Å reveals a tunnel …

Twisting and Protonation of Retinal Chromophore Regulate Channel Gating of Channelrhodopsin C1C2

K Shibata, K Oda, T Nishizawa, Y Hazama… - Journal of the …, 2023 - ACS Publications
Channelrhodopsins (ChRs) are light-gated ion channels and central optogenetic tools that
can control neuronal activity with high temporal resolution at the single-cell level. Although …

Demonstration of a Light-Driven SO42– Transporter and Its Spectroscopic Characteristics

A Niho, S Yoshizawa, T Tsukamoto… - Journal of the …, 2017 - ACS Publications
In organisms, ion transporters play essential roles in the generation and dissipation of ion
gradients across cell membranes. Microbial rhodopsins selectively transport cognate ions …