Forkhead box proteins: tuning forks for transcriptional harmony

EWF Lam, JJ Brosens, AR Gomes, CY Koo - Nature Reviews Cancer, 2013 - nature.com
Forkhead box (FOX) proteins are multifaceted transcription factors that are responsible for
fine-tuning the spatial and temporal expression of a broad range of genes both during …

[HTML][HTML] WNT signaling in glioblastoma and therapeutic opportunities

Y Lee, JK Lee, SH Ahn, J Lee, DH Nam - Laboratory investigation, 2016 - Elsevier
WNTs and their downstream effectors regulate proliferation, death, and migration and cell
fate decision. Deregulation of WNT signaling is associated with various cancers including …

Novel role of FBXW7 circular RNA in repressing glioma tumorigenesis

Y Yang, X Gao, M Zhang, S Yan, C Sun… - JNCI: Journal of the …, 2018 - academic.oup.com
Abstract Background Circular RNAs (circRNAs) are RNA transcripts that are widespread in
the eukaryotic genome. Recent evidence indicates that circRNAs play important roles in …

Multiomics analyses reveal DARS1-AS1/YBX1–controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance

C Zheng, Y Wei, Q Zhang, M Sun, Y Wang, J Hou… - Science …, 2023 - science.org
The glioblastoma (GBM) stem cell–like cells (GSCs) are critical for tumorigenesis/therapeutic
resistance of GBM. Mounting evidence supports tumor-promoting function of long noncoding …

[HTML][HTML] The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

S Yao, LYN Fan, EWF Lam - Seminars in cancer biology, 2018 - Elsevier
The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the
essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell …

[HTML][HTML] FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance

S Zona, L Bella, MJ Burton, GN de Moraes… - Biochimica Et Biophysica …, 2014 - Elsevier
FOXM1 is a transcription factor required for a wide spectrum of essential biological functions,
including DNA damage repair, cell proliferation, cell cycle progression, cell renewal, cell …

FoxM1: Repurposing an oncogene as a biomarker

D Nandi, PS Cheema, N Jaiswal, A Nag - Seminars in Cancer Biology, 2018 - Elsevier
The past few decades have witnessed a tremendous progress in understanding the biology
of cancer, which has led to more comprehensive approaches for global gene expression …

RAD51 is a selective DNA repair target to radiosensitize glioma stem cells

HO King, T Brend, HL Payne, A Wright, TA Ward… - Stem cell reports, 2017 - cell.com
Patients with glioblastoma die from local relapse despite surgery and high-dose
radiotherapy. Resistance to radiotherapy is thought to be due to efficient DNA double-strand …

The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …

FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …