Making waves: New developments in toxicology with the zebrafish

KA Horzmann, JL Freeman - Toxicological Sciences, 2018 - academic.oup.com
The laboratory zebrafish (Danio rerio) is now an accepted model in toxicologic research.
The zebrafish model fills a niche between in vitro models and mammalian biomedical …

An ecotoxicological view on neurotoxicity assessment

JB Legradi, C Di Paolo, MHS Kraak… - Environmental Sciences …, 2018 - Springer
The numbers of potential neurotoxicants in the environment are raising and pose a great risk
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …

Evaluation of developmental toxicity, developmental neurotoxicity, and tissue dose in zebrafish exposed to GenX and other PFAS

S Gaballah, A Swank, JR Sobus… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …

The Eco‐Exposome concept: Supporting an integrated assessment of mixtures of environmental chemicals

S Scholz, JW Nichols, BI Escher… - Environmental …, 2022 - Wiley Online Library
Organisms are exposed to ever‐changing complex mixtures of chemicals over the course of
their lifetime. The need to more comprehensively describe this exposure and relate it to …

Psychoactive pharmaceuticals and illicit drugs in coastal waters of North-Western Spain: Environmental exposure and risk assessment

J Fernández-Rubio, JL Rodríguez-Gil, C Postigo… - Chemosphere, 2019 - Elsevier
The knowledge on the presence of pharmaceutical compounds, and possible risks, in
coastal and marine systems is still limited. This study represents the first attempt at …

Toxicokinetics of Perfluorinated Alkyl Acids Influences Their Toxic Potency in the Zebrafish Embryo (Danio rerio)

C Vogs, G Johanson, M Näslund, S Wulff… - … science & technology, 2019 - ACS Publications
Perfluorinated alkyl acids (PFAA) are highly persistent and bioaccumulative and have been
associated with several adverse health effects. The chemical structure mainly differs in two …

Bioconcentration of neuroactive pharmaceuticals in fish: Relation to lipophilicity, experimental design and toxicity in the aquatic environment

IA Duarte, J Fick, HN Cabral, VF Fonseca - Science of the Total …, 2022 - Elsevier
Uptake of contaminants is linked to their toxicity and is usually estimated through their
lipophilicity (logK ow). Here, we review current literature regarding bioconcentration, ie …

Biological effects of the benzotriazole ultraviolet stabilizers UV-234 and UV-320 in early-staged zebrafish (Danio rerio)

X Liang, O Adamovsky, CL Souders II… - Environmental pollution, 2019 - Elsevier
Among the benzotriazole ultraviolet stabilizers (BUVSs), UV-234 and UV-320 are frequently
detected in aquatic ecosystem. Despite the fact that these chemicals are present in low ng/L …

Effects of acetochlor on neurogenesis and behaviour in zebrafish at early developmental stages

H Wang, Z Meng, L Zhou, Z Cao, X Liao, R Ye, H Lu - Chemosphere, 2019 - Elsevier
The herbicide acetochlor is used in most parts of the world and is frequently detected in
agricultural land and surface water; however, knowledge on the neurotoxicity of acetochlor …

Developmental Effects of Cannabidiol and Δ9-Tetrahydrocannabinol in Zebrafish

DR Carty, C Thornton, JH Gledhill… - Toxicological …, 2018 - academic.oup.com
Cannabidiol (CBD) has gained much attention in the past several years for its therapeutic
potential in the treatment of drug-resistant epilepsy, such as Dravet syndrome. Although …