[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …
Small molecule anti-biofilm agents developed on the basis of mechanistic understanding of biofilm formation
K Qvortrup, LD Hultqvist, M Nilsson… - Frontiers in …, 2019 - frontiersin.org
Microbial biofilms are the cause of persistent infections associated with various medical
implants and distinct body sites such as the urinary tract, lungs, and wounds. Compared with …
implants and distinct body sites such as the urinary tract, lungs, and wounds. Compared with …
Pyoverdine-Dependent Virulence of Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients
The development of therapies that modulate or prevent pathogen virulence may be a key
strategy for circumventing antimicrobial resistance. Toward that end, we examined the …
strategy for circumventing antimicrobial resistance. Toward that end, we examined the …
Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa
D Kang, NV Kirienko - Journal of microbiology, 2018 - Springer
Bacterial biofilms remain a persistent threat to human healthcare due to their role in the
development of antimicrobial resistance. To combat multi-drug resistant pathogens, it is …
development of antimicrobial resistance. To combat multi-drug resistant pathogens, it is …
Pseudomonas Quinolone Signal-Induced Outer Membrane Vesicles Enhance Biofilm Dispersion in Pseudomonas aeruginosa
Bacterial biofilms are major contributors to chronic infections in humans. Because they are
recalcitrant to conventional therapy, they present a particularly difficult treatment challenge …
recalcitrant to conventional therapy, they present a particularly difficult treatment challenge …
Age of Antibiotic Resistance in MDR/XDR Clinical Pathogen of Pseudomonas aeruginosa
A Kothari, R Kherdekar, V Mago, M Uniyal, G Mamgain… - Pharmaceuticals, 2023 - mdpi.com
Antibiotic resistance in Pseudomonas aeruginosa remains one of the most challenging
phenomena of everyday medical science. The universal spread of high-risk clones of …
phenomena of everyday medical science. The universal spread of high-risk clones of …
Novel insights on pyoverdine: from biosynthesis to biotechnological application
Pyoverdines (PVDs) are a class of siderophores produced mostly by members of the genus
Pseudomonas. Their primary function is to accumulate, mobilize, and transport iron …
Pseudomonas. Their primary function is to accumulate, mobilize, and transport iron …
Cheminformatics Bioprospection of Sunflower Seeds' Oils against Quorum Sensing System of Pseudomonas aeruginosa
NW S'thebe, JO Aribisala, S Sabiu - Antibiotics, 2023 - mdpi.com
Clinically significant pathogens such as Pseudomonas aeruginosa evade the effects of
antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a …
antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a …
A small-molecule inhibitor of the anthranilyl-CoA synthetase PqsA for the treatment of multidrug-resistant Pseudomonas aeruginosa
J Chen, Y Lu, F Ye, H Zhang, Y Zhou, J Li… - Microbiology …, 2022 - Am Soc Microbiol
One of the challenges associated with the treatment of Pseudomonas aeruginosa infections
is the high prevalence of multidrug resistance (MDR). Since conventional antibiotics are …
is the high prevalence of multidrug resistance (MDR). Since conventional antibiotics are …
Structural analysis of novel drug targets for mitigation of Pseudomonas aeruginosa biofilms
M Ghosh, S Raghav, P Ghosh, S Maity… - FEMS Microbiology …, 2023 - academic.oup.com
Pseudomonas aeruginosa is an opportunistic human pathogen responsible for acute and
chronic, hard to treat infections. Persistence of P. aeruginosa is due to its ability to develop …
chronic, hard to treat infections. Persistence of P. aeruginosa is due to its ability to develop …