Management of coronary artery disease in older adults: recent advances and gaps in evidence

S Cacciatore, L Spadafora, M Bernardi, M Galli… - Journal of clinical …, 2023 - mdpi.com
Coronary artery disease (CAD) is highly prevalent in older adults, yet its management
remains challenging. Treatment choices are made complex by the frailty burden of older …

Shorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention: A Systematic Review and Network Meta-Analysis

DY Park, JR Hu, Y Jamil, MD Kelsey… - JAMA Network …, 2024 - jamanetwork.com
Importance The optimal duration of dual antiplatelet therapy (DAPT) for older adults after
percutaneous coronary intervention (PCI) is uncertain because they are simultaneously at …

Beyond MACE: a multidimensional approach to outcomes in clinical trials for older adults with stable ischemic heart disease

K Kalra, MB Moumneh, MG Nanna… - Frontiers in …, 2023 - frontiersin.org
The global population of older adults is expanding rapidly resulting in a shift towards
managing multiple chronic diseases that coexist and may be exacerbated by cardiovascular …

Chronological vs Biological Age in Interventional Cardiology: A Comprehensive Approach to Care for Older Adults: JACC Family Series

AA Damluji, MG Nanna, J Rymer, A Kochar… - Cardiovascular …, 2024 - jacc.org
Aging is the gradual decline in physical and physiological functioning leading to increased
susceptibility to stressors and chronic illnesses, including cardiovascular disease. With an …

Chronic Coronary Disease in Older Adults

AP Ambrosini, ES Fishman, AA Damluji… - Medical …, 2024 - medical.theclinics.com
Chronic coronary disease (CCD) is a major cause of morbidity and mortality in older adults.
1, 2 Despite this, older adults are underrepresented in the current literature supporting …

Ticagrelor 60 vs. 90 mg in Elderly ACS Patients undergoing PCI: a Randomized, Crossover Trial

R Piccolo, F Simonetti, M Avvedimento… - European Heart …, 2024 - academic.oup.com
Aims Although dual antiplatelet therapy (DAPT) with aspirin and a potent P2Y12 receptor
inhibitor is currently recommended in patients with acute coronary syndrome (ACS), its use …