Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …

Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …

Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …

The development of mature blood cells from haematopoietic stem cells has long served as a
model for stem-cell research, with the haematopoietic differentiation tree being widely used …

Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

Dendritic cells (DC) are specialized immune cells that play a critical role in promoting an
immune response against Ags, which can include foreign pathogenic Ags and self-tumor …

Despite breakthroughs in immune checkpoint inhibitor (ICI) immunotherapy, not all human
cancers respond to ICI immunotherapy and a large fraction of patients with the responsive …

Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs,
comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear. We …

The formation of mammalian dendritic cells (DCs) is controlled by multiple hematopoietic
transcription factors, including IRF8. Loss of IRF8 exerts a differential effect on DC subsets …