Toroidal DNA condensates: unraveling the fine structure and the role of nucleation in determining size

NV Hud, ID Vilfan - Annu. Rev. Biophys. Biomol. Struct., 2005 - annualreviews.org
▪ Abstract Toroidal DNA condensates have attracted the attention of biophysicists,
biochemists, and polymer physicists for more than thirty years. In the biological community …

Compaction of bacterial genomic DNA: clarifying the concepts

M Joyeux - Journal of Physics: Condensed Matter, 2015 - iopscience.iop.org
The unconstrained genomic DNA of bacteria forms a coil, whose volume exceeds 1000
times the volume of the cell. Since prokaryotes lack a membrane-bound nucleus, in sharp …

Controlling the size of nanoscale toroidal DNA condensates with static curvature and ionic strength

CC Conwell, ID Vilfan, NV Hud - Proceedings of the …, 2003 - National Acad Sciences
The process of DNA condensation into nanometer-scale particles has direct relevance to
several fields, including cell biology, virology, and gene delivery for therapeutic purposes …

Sucking genes into pores: Insight into driven translocation

T Sakaue - Physical Review E—Statistical, Nonlinear, and Soft …, 2010 - APS
Flexible polymers such as long DNA, RNA molecules, and proteins, can pass through a
narrow pore whose size is comparable to their molecular thickness. We highlight the …

Competing single-chain folding and multi-chain aggregation pathways control solution-phase aggregate morphology of organic semiconducting polymers

BJ Boehm, CR McNeill, DM Huang - Nanoscale, 2022 - pubs.rsc.org
Understanding the solution-phase behaviour of organic semiconducting polymers is
important for systematically improving the performance of devices based on solution …

Collapse of a semiflexible polymer in poor solvent

A Montesi, M Pasquali, FC MacKintosh - Physical Review E, 2004 - APS
We investigate the dynamics and pathways of the collapse of a single, semiflexible polymer
in a poor solvent via three-dimensional Brownian Dynamics simulations. An example of this …

The persistence length of semiflexible polymers in lattice Monte Carlo simulations

JZ Zhang, XY Peng, S Liu, BP Jiang, SC Ji, XC Shen - Polymers, 2019 - mdpi.com
While applying computer simulations to study semiflexible polymers, it is a primary task to
determine the persistence length that characterizes the chain stiffness. One frequently asked …

Linker histone H1 per se can induce three-dimensional folding of chromatin fiber

K Hizume, SH Yoshimura, K Takeyasu - Biochemistry, 2005 - ACS Publications
Higher-order architectures of chromosomes play important roles in the regulation of genome
functions. To understand the molecular mechanism of genome packing, an in vitro chromatin …

Time study of DNA condensate morphology: implications regarding the nucleation, growth, and equilibrium populations of toroids and rods

ID Vilfan, CC Conwell, T Sarkar, NV Hud - Biochemistry, 2006 - ACS Publications
It is well known that multivalent cations cause free DNA in solution to condense into
nanometer-scale particles with toroidal and rod-like morphologies. However, it has not been …

Hierarchical Self-Assembly of Poly(d-glucose carbonate) Amphiphilic Block Copolymers in Mixed Solvents

JY Lee, Y Song, MG Wessels, A Jayaraman… - …, 2020 - ACS Publications
We report the fibril formation of poly (d-glucose carbonate)(PGC)-based amphiphilic diblock
copolymers using solution assembly. Unlike conventional cylindrical micelles constructed …