Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Limosilactobacillus fermentum JL-3 isolated from “Jiangshui” ameliorates hyperuricemia by degrading uric acid

Y Wu, Z Ye, P Feng, R Li, X Chen, X Tian, R Han… - Gut …, 2021 - Taylor & Francis
Recent studies into the beneficial effects of fermented foods have shown that this class of
foods are effective in managing hyperuricemia and gout. In this study, the uric acid (UA) …

[HTML][HTML] The treatment of hyperuricemia

M Gliozzi, N Malara, S Muscoli, V Mollace - International journal of …, 2016 - Elsevier
Hyperuricemia has long been established as the major etiologic factor in gout. Alongside
with an inflammatory state triggered by urate crystal deposition in the joints, hyperuricemia …

Gout and hyperuricaemia in the USA: prevalence and trends

G Singh, B Lingala, A Mithal - Rheumatology, 2019 - academic.oup.com
Objectives Several recent observations have suggested that the prevalence of gout may be
increasing worldwide, but there are no recent data from the USA. We analysed the …

Biomarkers of oxidative stress tethered to cardiovascular diseases

P Panda, HK Verma, S Lakkakula… - Oxidative Medicine …, 2022 - Wiley Online Library
Cardiovascular disease (CVD) is a broad term that incorporated a group of conditions that
affect the blood vessels and the heart. CVD is a foremost cause of fatalities around the …

[HTML][HTML] Hyperuricemia-related diseases and xanthine oxidoreductase (XOR) inhibitors: an overview

C Chen, JM Lü, Q Yao - Medical science monitor: international …, 2016 - ncbi.nlm.nih.gov
Uric acid is the final oxidation product of purine metabolism in humans. Xanthine
oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric …

[PDF][PDF] Is it time to revise the normal range of serum uric acid levels?

G Desideri, G Castaldo, A Lombardi… - European Review for …, 2014 - europeanreview.org
The actual reference range of serum uric acid has been assessed according to its variations
among healthy individuals. ie those without clinical evidence of gout. By this approach …

Oxidative stress in cell death and cardiovascular diseases

T Xu, W Ding, X Ji, X Ao, Y Liu, W Yu… - Oxidative medicine and …, 2019 - Wiley Online Library
ROS functions as a second messenger and modulates multiple signaling pathways under
the physiological conditions. However, excessive intracellular ROS causes damage to the …