Postural orthostatic tachycardia syndrome (POTS), the most common form of orthostatic
intolerance in young people, affects approximately 500,000 people in the United States …

Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

• Countermeasures before, during and after space flight are essential to reduce health risks.•
Although most physiologic effects resolve shortly after return to earth, bone demineralization …

Objectives: The purpose of this study was to test the hypothesis that a small heart coupled
with reduced blood volume contributes to the postural orthostatic tachycardia syndrome …

Dry immersion, which is a ground-based model of prolonged conditions of microgravity, is
widely used in Russia but is less well known elsewhere. Dry immersion involves immersing …

Large, reproducible interindividual differences exist in resting sympathetic nerve activity
among normotensive humans with similar arterial pressures, resulting in a lack of correlation …

Humans are generally in standing or sitting positions on Earth during the day. The
musculoskeletal system supports these positions and also allows motion. Gravity acting in …

The abnormal physiology that manifests itself in healthy humans during their adaptation to
the microgravity of space has all the features of accelerated aging. The mechano-skeletal …

Impaired autonomic control represents a cardiovascular risk factor during long-term
spaceflight. Little has been reported on blood pressure (BP), heart rate (HR), and heart rate …

We have found recently that exercise training is effective in the treatment of the postural
orthostatic tachycardia syndrome (POTS). Whether this nondrug treatment is superior to …