Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis
where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due …

E-cadherin is a transmembrane glycoprotein which connects epithelial cells together at
adherens junctions. In normal cells, E-cadherin exerts its tumour suppressing role mainly by …

The epithelial to mesenchymal transition (EMT) is a biological process in which a non-motile
epithelial cell changes to a mesenchymal phenotype with invasive capacities. This …

The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …

Tumors often show, compared to normal tissues, a markedly decreased extracellular pH
resulting from anaerobic or aerobic glycolysis in combination with a reduced removal of …

Metastasis is responsible for most cancer-related deaths, but the current clinical treatments
are not effective. Recently, gold nanoparticles (AuNPs) were discovered to inhibit cancer cell …

The epithelial–mesenchymal transition (EMT) is thought to be at the root of invasive and
metastatic cancer cell spreading. E-cadherin is an important player in this process, which …

Melanoma is a cutaneous neoplastic growth of melanocytes with great potential to invade
and metastasize, especially when not treated early and effectively. Epithelial-mesenchymal …

Gene fusions and their products (RNA and protein) were once thought to be unique features
to cancer. However, chimeric RNAs can also be found in normal cells. Here, we performed …

For decades, the aryl hydrocarbon receptor (AHR) was studied for its role in environmental
chemical toxicity ie, as a quirk of nature and a mediator of unintended consequences of …