[HTML][HTML] L-theanine: A unique functional amino acid in tea (Camellia sinensis L.) with multiple health benefits and food applications

MY Li, HY Liu, DT Wu, A Kenaan, F Geng, HB Li… - Frontiers in …, 2022 - frontiersin.org
Tea (Camellia sinensis L.) is a very popular health drink and has attracted increasing
attention in recent years due to its various bioactive substances. Among them, L-theanine, a …

Insight into the emerging role of striatal neurotransmitters in the pathophysiology of Parkinson's disease and Huntington's disease: a review

S Jamwal, P Kumar - Current neuropharmacology, 2019 - ingentaconnect.com
Alteration in neurotransmitters signaling in basal ganglia has been consistently shown to
significantly contribute to the pathophysiological basis of Parkinson's disease and …

Protective Effect of l-Theanine against DSS-Induced Colitis by Regulating the Lipid Metabolism and Reducing Inflammation via the NF-κB Signaling Pathway

L Zhang, X Yao, M Ma, Y Ding, H Zhang… - Journal of Agricultural …, 2021 - ACS Publications
The present study revealed the phylactic effects of l-theanine on a DSS-induced colitis mice
model. The results showed that 3% DSS treatment significantly induced intestinal damage …

Neuroprotective effects and mechanisms of tea bioactive components in neurodegenerative diseases

SQ Chen, ZS Wang, YX Ma, W Zhang, JL Lu, YR Liang… - Molecules, 2018 - mdpi.com
As the population ages, neurodegenerative diseases such as Parkinson's disease (PD) and
Alzheimer's disease (AD) impose a heavy burden on society and families. The …

[HTML][HTML] L-theanine: an astounding sui generis amino acid in poultry nutrition

M Saeed, MS Khan, AA Kamboh, M Alagawany… - Poultry science, 2020 - Elsevier
Abstract L-theanine (γ-Glutamylethylamide) is a nonprotein water soluble amino acid (AA)
mostly found in leaves of Camellia sinensis (green tea). This is a key component of green …

Rutin and selenium co-administration reverse 3-nitropropionic acid-induced neurochemical and molecular impairments in a mouse model of Huntington's disease

MS Abdelfattah, SEA Badr, SA Lotfy, GH Attia… - Neurotoxicity …, 2020 - Springer
Systemic administration of 3-nitropropionic acid (3-NPA) is commonly used to induce
Huntington's disease (HD)-like symptoms in experimental animals. Here, the potential …

An overview of the pathophysiological mechanisms of 3-nitropropionic acid (3-NPA) as a neurotoxin in a huntington's disease model and its relevance to drug …

S Upadhayay, NG Yedke, V Rahi, S Singh… - Neurochemical …, 2023 - Springer
Animal models are used to better understand the various mechanisms involved in the
pathogenesis of diseases and explore potential pathways that will aid in discovering …

Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced …

S Ahmed, M Kwatra, B Gawali, SR Panda, VGM Naidu - Apoptosis, 2021 - Springer
Striatal neurons depends on an afferent supply of brain-derived neurotrophic factor-(BDNF)
that explicitly interacts with tropomyosin receptor kinase B (TrkB) receptor and performs …

L-theanine reduced the development of knee osteoarthritis in rats via its anti-inflammation and anti-matrix degradation actions: in vivo and in vitro study

H Bai, Z Zhang, Y Li, X Song, T Ma, C Liu, L Liu… - Nutrients, 2020 - mdpi.com
The etiology of osteoarthritis (OA) is multifactorial, with no effective disease-modifying-drugs.
L-theanine has been reported to inhibit inflammatory responses in some diseases and this …

Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington's disease via suppressing MAPKs and NF-κB pathways …

X Yang, S Chu, Z Wang, F Li, Y Yuan… - Acta Pharmacologica …, 2021 - nature.com
Huntington's disease (HD) is one of main neurodegenerative diseases, characterized by
striatal atrophy, involuntary movements, and motor incoordination. Ginsenoside Rg1 (Rg1) …