Bioconjugated quantum dots for in vivo molecular and cellular imaging

AM Smith, H Duan, AM Mohs, S Nie - Advanced drug delivery reviews, 2008 - Elsevier
Semiconductor quantum dots (QDs) are tiny light-emitting particles on the nanometer scale,
and are emerging as a new class of fluorescent labels for biology and medicine. In …

Probing cellular events, one quantum dot at a time

F Pinaud, S Clarke, A Sittner, M Dahan - Nature methods, 2010 - nature.com
Monitoring the behavior of single molecules in living cells is a powerful approach to
investigate the details of cellular processes. Owing to their optical, chemical and …

Cadmium-containing quantum dots: properties, applications, and toxicity

D Mo, L Hu, G Zeng, G Chen, J Wan, Z Yu… - Applied microbiology …, 2017 - Springer
The marriage of biology with nanomaterials has significantly accelerated advancement of
biological techniques, profoundly facilitating practical applications in biomedical fields. With …

Nanoparticulate systems for growth factor delivery

S Zhang, H Uludağ - Pharmaceutical research, 2009 - Springer
The field of nanotechnology, which aims to control and utilize matter generally in 1–100 nm
range, has been at the forefront of pharmaceutical development. Nanoparticulate delivery …

Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease

C Faustino, P Rijo, CP Reis - Pharmacological research, 2017 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
amyloid-β peptide misfolding and aggregation. Neurotrophic factors, such as nerve growth …

Coordination of molecular motors: from in vitro assays to intracellular dynamics

ELF Holzbaur, YE Goldman - Current opinion in cell biology, 2010 - Elsevier
New technologies have emerged that enable the tracking of molecular motors and their
cargos with very high resolution both in vitro and in live cells. Classic in vitro motility assays …

Stable small quantum dots for synaptic receptor tracking on live neurons

E Cai, P Ge, SH Lee, O Jeyifous, Y Wang… - Angewandte …, 2014 - Wiley Online Library
We developed a coating method to produce functionalized small quantum dots (sQDs),
about 9 nm in diameter, that were stable for over a month. We made sQDs in four emission …

Neurotrophin signaling via long-distance axonal transport

PD Chowdary, DL Che, B Cui - Annual review of physical …, 2012 - annualreviews.org
Neurotrophins are a family of target-derived growth factors that support survival,
development, and maintenance of innervating neurons. Owing to the unique architecture of …

Ligand-bound quantum dot probes for studying the molecular scale dynamics of receptor endocytic trafficking in live cells

SS Rajan, HY Liu, TQ Vu - ACS nano, 2008 - ACS Publications
Endocytic receptor trafficking is a complex, dynamic process underlying fundamental cell
function. An integrated understanding of endocytosis at the level of single or small numbers …

Local synthesis of dynein cofactors matches retrograde transport to acutely changing demands

JM Villarin, EP McCurdy, JC Martínez… - Nature communications, 2016 - nature.com
Cytoplasmic dynein mediates retrograde transport in axons, but it is unknown how its
transport characteristics are regulated to meet acutely changing demands. We find that …