[HTML][HTML] How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow …
Background Knee replacements are the mainstay of treatment for end-stage osteoarthritis
and are effective. Given time, all knee replacements will fail and knowing when this failure …
and are effective. Given time, all knee replacements will fail and knowing when this failure …
[HTML][HTML] Psychiatric disorders in refugees and internally displaced persons after forced displacement: a systematic review
Background: Protracted armed conflicts not only shape political, legal, and socio-economic
structures, but also have a lasting impact on people's human migration. In 2017, the United …
structures, but also have a lasting impact on people's human migration. In 2017, the United …
[HTML][HTML] Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer
F Schettini, N Chic, F Brasó-Maristany, L Paré… - NPJ breast …, 2021 - nature.com
Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative
breast cancer (BC) with low HER2 expression (ie, 1+ or 2+ and lack of ERBB2 amplification) …
breast cancer (BC) with low HER2 expression (ie, 1+ or 2+ and lack of ERBB2 amplification) …
Risk factors for coronavirus disease 2019 (COVID-19) death in a population cohort study from the Western Cape Province, South Africa
Clinical Infectious Diseases, 2021 - academic.oup.com
Background Risk factors for coronavirus disease 2019 (COVID-19) death in sub-Saharan
Africa and the effects of human immunodeficiency virus (HIV) and tuberculosis on COVID-19 …
Africa and the effects of human immunodeficiency virus (HIV) and tuberculosis on COVID-19 …
[HTML][HTML] Descriptive statistics and normality tests for statistical data
Descriptive statistics are an important part of biomedical research which is used to describe
the basic features of the data in the study. They provide simple summaries about the sample …
the basic features of the data in the study. They provide simple summaries about the sample …
A checklist for statistical assessment of medical papers (the CHAMP statement): explanation and elaboration
Misuse of statistics in medical and sports science research is common and may lead to
detrimental consequences to healthcare. Many authors, editors and peer reviewers of …
detrimental consequences to healthcare. Many authors, editors and peer reviewers of …
A practical primer to power analysis for simple experimental designs
Power analysis is an important tool to use when planning studies. This contribution aims to
remind read-ers what power analysis is, emphasize why it matters, and articulate when and …
remind read-ers what power analysis is, emphasize why it matters, and articulate when and …
Image-to-image regression with distribution-free uncertainty quantification and applications in imaging
Image-to-image regression is an important learning task, used frequently in biological
imaging. Current algorithms, however, do not generally offer statistical guarantees that …
imaging. Current algorithms, however, do not generally offer statistical guarantees that …
Modifiable risk factors associated with cardiovascular disease and mortality in China: a PURE substudy
Aims To examine the incidence of cardiovascular disease (CVD) and mortality in China and
in key subpopulations, and to estimate the population-level risks attributable to 12 common …
in key subpopulations, and to estimate the population-level risks attributable to 12 common …
Tebentafusp, a TCR/anti-CD3 bispecific fusion protein targeting gp100, potently activated antitumor immune responses in patients with metastatic melanoma
MR Middleton, C McAlpine, VK Woodcock… - Clinical Cancer …, 2020 - AACR
Purpose: Tebentafusp is a first-in-class bispecific fusion protein designed to target gp100 (a
melanoma-associated antigen) through a high affinity T-cell receptor (TCR) binding domain …
melanoma-associated antigen) through a high affinity T-cell receptor (TCR) binding domain …