A review of methods and databases for metagenomic classification and assembly
Microbiome research has grown rapidly over the past decade, with a proliferation of new
methods that seek to make sense of large, complex data sets. Here, we survey two of the …
methods that seek to make sense of large, complex data sets. Here, we survey two of the …
Metagenomic approaches in microbial ecology: an update on whole-genome and marker gene sequencing analyses
AE Pérez-Cobas, L Gomez-Valero… - Microbial …, 2020 - microbiologyresearch.org
Metagenomics and marker gene approaches, coupled with high-throughput sequencing
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …
metaSPAdes: a new versatile metagenomic assembler
While metagenomics has emerged as a technology of choice for analyzing bacterial
populations, the assembly of metagenomic data remains challenging, thus stifling biological …
populations, the assembly of metagenomic data remains challenging, thus stifling biological …
MaxBin 2.0: an automated binning algorithm to recover genomes from multiple metagenomic datasets
The recovery of genomes from metagenomic datasets is a critical step to defining the
functional roles of the underlying uncultivated populations. We previously developed …
functional roles of the underlying uncultivated populations. We previously developed …
MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities
Grouping large genomic fragments assembled from shotgun metagenomic sequences to
deconvolute complex microbial communities, or metagenome binning, enables the study of …
deconvolute complex microbial communities, or metagenome binning, enables the study of …
MaxBin: an automated binning method to recover individual genomes from metagenomes using an expectation-maximization algorithm
Background Recovering individual genomes from metagenomic datasets allows access to
uncultivated microbial populations that may have important roles in natural and engineered …
uncultivated microbial populations that may have important roles in natural and engineered …
MetaVelvet: an extension of Velvet assembler to de novo metagenome assembly from short sequence reads
T Namiki, T Hachiya, H Tanaka… - Proceedings of the 2nd …, 2011 - dl.acm.org
Motivation: An important step of" metagenomics" analysis is the assembly of multiple
genomes from mixed sequence reads of multiple species in a microbial community. Most …
genomes from mixed sequence reads of multiple species in a microbial community. Most …
High throughput sequencing methods and analysis for microbiome research
High-throughput sequencing technology is rapidly improving in quality, speed and cost. It is
therefore becoming more widely used to study whole communities of prokaryotes in many …
therefore becoming more widely used to study whole communities of prokaryotes in many …
Meta-IDBA: a de Novo assembler for metagenomic data
Motivation: Next-generation sequencing techniques allow us to generate reads from a
microbial environment in order to analyze the microbial community. However, assembling of …
microbial environment in order to analyze the microbial community. However, assembling of …
Gut dysbiosis and muscle aging: searching for novel targets against sarcopenia
Advanced age is characterized by several changes, one of which is the impairment of the
homeostasis of intestinal microbiota. These alterations critically influence host health and …
homeostasis of intestinal microbiota. These alterations critically influence host health and …