Polysaccharide-based hydrogels and their application as drug delivery systems in cancer treatment: a review

M Dattilo, F Patitucci, S Prete, OI Parisi… - Journal of Functional …, 2023 - mdpi.com
Hydrogels are three-dimensional crosslinked structures with physicochemical properties
similar to the extracellular matrix (ECM). By changing the hydrogel's material type …

Recent advances in nanotechnology-based drug delivery systems for the kidney

F Oroojalian, F Charbgoo, M Hashemi, A Amani… - Journal of controlled …, 2020 - Elsevier
The application of nanotechnology in medicine has the potential to make a great impact on
human health, ranging from prevention to diagnosis and treatment of disease. The kidneys …

Low expression of ferritinophagy-related NCOA4 gene in relation to unfavorable outcome and defective immune cells infiltration in clear cell renal carcinoma

Y Mou, J Wu, Y Zhang, O Abdihamid, C Duan, B Li - BMC cancer, 2021 - Springer
Background Clear cell renal cell carcinoma is susceptible to ferroptosis, and immunotherapy
is recently recommended as a priority for the initial treatment of metastatic clear cell renal …

Anticancer activity of rutin and its combination with ionic liquids on renal cells

R Caparica, A Júlio, MEM Araújo, AR Baby, P Fonte… - Biomolecules, 2020 - mdpi.com
The renal cell carcinoma (RCC) is the most common type of kidney cancer. Identifying novel
and more effective therapies, while minimizing toxicity, continues to be fundamental in …

The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics

MYW Ng, C Charsou, A Lapao, S Singh… - Nature …, 2022 - nature.com
During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called
autophagosomes. The contributions of specific lipids, such as cholesterol, to the membranes …

Health benefits of resveratrol in kidney disease: evidence from in vitro and in vivo studies

DJ Den Hartogh, E Tsiani - Nutrients, 2019 - mdpi.com
Different diseases and disorders that affect the kidneys include, but are not limited to,
glomerulonephritis, diabetic nephropathy, polycystic kidney disease, kidney stones, renal …

Knowledge mapping and research hotspots of immunotherapy in renal cell carcinoma: A text-mining study from 2002 to 2021

K Liu, S Zhao, J Li, Y Zheng, H Wu, J Kong… - Frontiers in …, 2022 - frontiersin.org
Background Renal cell carcinoma (RCC) is one of the most lethal urological malignancies,
and because early-stage RCC is asymptomatic, many patients present metastatic diseases …

PI3K/AKT/mTOR dysregulation and reprogramming metabolic pathways in renal cancer: Crosstalk with the VHL/HIF axis

SC Badoiu, M Greabu, D Miricescu… - International journal of …, 2023 - mdpi.com
Renal cell carcinoma (RCC) represents 85–95% of kidney cancers and is the most frequent
type of renal cancer in adult patients. It accounts for 3% of all cancer cases and is in 7th …

Epigenetic modifiers: activities in renal cell carcinoma

AA De Cubas, WK Rathmell - Nature Reviews Urology, 2018 - nature.com
Renal cell carcinomas (RCCs) are a diverse set of malignancies that have recently been
shown to harbour mutations in a number of chromatin modifier genes—including PBRM1 …

Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis

J Yang, Y Zhou, Y Li, W Hu, C Yuan, S Chen, G Ye… - …, 2022 - Taylor & Francis
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinomas,
with high mortality and poor prognoses worldwide. Succinate dehydrogenase (SDH) …