Alveolar type 2 progenitor cells (AT2) seem closest to clinical translation, specifying the
evidence that AT2 may satisfactorily control the immune response to decrease lung injury by …

Helicobacter infection is the leading cause of gastric cancer worldwide. Infection with this
ubiquitous bacterium incites a chronic active immune response that persists for the life of the …

Injury models have suggested that the lung contains anatomically and functionally distinct
epithelial stem cell populations. We have isolated such a regional pulmonary stem cell …

Background The acute respiratory distress syndrome (ARDS), a clinical complication of
severe acute lung injury (ALI) in humans, is a leading cause of morbidity and mortality in …

Although regenerative medicine is searching for pluripotent stem cells that could be
employed for therapy, various types of more differentiated adult stem and progenitor cells …

By employing multiparameter sorting, we identified in murine bone marrow (BM) a
homogenous population of rare (∼ 0.02% of BMMNC) Sca-1+ lin− CD45− cells that express …

Rationale: Bronchopulmonary dysplasia (BPD) and emphysema are characterized by
arrested alveolar development or loss of alveoli; both are significant global health problems …

Hepatic transdifferentiation of bone marrow cells has been previously demonstrated by
intravenous administration of donor cells, which may recirculate to the liver after undergoing …

Embryonic stem cells (ES cells), bone marrow-derived mesenchymal stem cells, umbilical
cord blood-derived mesenchymal stem cells, and hepatic stem cells in liver have been …

Background & Aims Bone marrow (BM) cells may transdifferentiate into or fuse with organ
parenchymal cells. BM therapy shows promise in murine models of cirrhosis, and clinical …