[HTML][HTML] Coronas of micro/nano plastics: a key determinant in their risk assessments

J Cao, Q Yang, J Jiang, T Dalu, A Kadushkin… - Particle and Fibre …, 2022 - Springer
As an emerging pollutant in the life cycle of plastic products, micro/nanoplastics (M/NPs) are
increasingly being released into the natural environment. Substantial concerns have been …

Airborne transmission of COVID-19: aerosol dispersion, lung deposition, and virus-receptor interactions

YY Zuo, WE Uspal, T Wei - ACS nano, 2020 - ACS Publications
Coronavirus disease 2019 (COVID-19), due to infection by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is now causing a global pandemic. Aerosol …

[HTML][HTML] Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs

MP Lokugamage, D Vanover, J Beyersdorf… - Nature biomedical …, 2021 - nature.com
Lipid nanoparticles (LNPs) for the efficient delivery of drugs need to be designed for the
particular administration route and type of drug. Here we report the design of LNPs for the …

Formation of a protein corona on the surface of extracellular vesicles in blood plasma

EÁ Tóth, L Turiák, T Visnovitz, C Cserép… - Journal of …, 2021 - Wiley Online Library
In this study we tested whether a protein corona is formed around extracellular vesicles
(EVs) in blood plasma. We isolated medium‐sized nascent EVs of THP1 cells as well as of …

Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona

H Tang, Y Zhang, T Yang, C Wang, Y Zhu, L Qiu… - Nature …, 2023 - nature.com
Nanoparticles (NPs) in biological fluids form a layer of biomolecules known as the protein
corona. The protein corona has been shown to determine the biological identity and in vivo …

Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery

W Kim, NK Ly, Y He, Y Li, Z Yuan, Y Yeo - Advanced drug delivery reviews, 2023 - Elsevier
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …

Converting nanotoxicity data to information using artificial intelligence and simulation

X Yan, T Yue, DA Winkler, Y Yin, H Zhu… - Chemical …, 2023 - ACS Publications
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

R Bilardo, F Traldi, A Vdovchenko… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …

Beyond PM2. 5: The role of ultrafine particles on adverse health effects of air pollution

R Chen, B Hu, Y Liu, J Xu, G Yang, D Xu… - Biochimica et Biophysica …, 2016 - Elsevier
Background Air pollution constitutes the major threat to human health, whereas their
adverse impacts and underlying mechanisms of different particular matters are not clearly …

[HTML][HTML] Understanding the lipid and protein corona formation on different sized polymeric nanoparticles

T Lima, K Bernfur, M Vilanova, T Cedervall - Scientific reports, 2020 - nature.com
When in contact with biological fluids, nanoparticles dynamically absorb biomolecules like
proteins and lipids onto their surface, forming a “corona”. This biocorona is a dynamic and …