Understanding of human brain development, dysfunction and neurological diseases has
remained limited and challenging due to inability to recapitulate human brain-specific …

The vascularization of engineered tissues and organoids has remained a major unresolved
challenge in regenerative medicine. While multiple approaches have been developed to …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

Identifying genes whose expression is associated with schizophrenia (SCZ) risk by
transcriptome-wide association studies (TWAS) facilitates downstream experimental studies …

Valproic acid (VPA) exposure during pregnancy leads to a higher risk of autism spectrum
disorder (ASD) susceptibility in offspring. Human dorsal forebrain organoids were used to …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder caused by
genetic or environmental perturbations during early development. Diagnoses are dependent …

Autism spectrum disorders (ASD) are a group of complex neurodevelopmental disorders
that affect communication and social interactions and present with restricted interests and …

Stem cell-derived organoid technology is a powerful tool that revolutionizes the field of
biomedical research and extends the scope of our understanding of human biology and …

The past decade has seen an explosion in the identification of genetic causes of
neurodevelopmental disorders, including Mendelian, de novo, and somatic factors. These …

Neurobiological disorders are highly prevalent medical conditions that contribute to
significant morbidity and mortality. Single-cell RNA sequencing (scRNA-seq) is a technique …