Alectinib in Resected ALK-Positive Non–Small-Cell Lung Cancer

YL Wu, R Dziadziuszko, JS Ahn, F Barlesi… - … England Journal of …, 2024 - Mass Medical Soc
Background Platinum-based chemotherapy is the recommended adjuvant treatment for
patients with resectable, ALK-positive non–small-cell lung cancer (NSCLC). Data on the …

Perioperative targeted therapy for oncogene-driven NSCLC

SY Liu, JT Zhang, KH Zeng, YL Wu - Lung Cancer, 2022 - Elsevier
Targeted therapy has stepped into the perioperative treatment arena and launched a radical
revolution in the treatment of early-stage oncogene-driven non-small-cell lung cancer …

A review of biomarkers and their clinical impact in resected early-stage non-small-cell lung cancer

W Cao, Q Tang, J Zeng, X Jin, L Zu, S Xu - Cancers, 2023 - mdpi.com
Simple Summary Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of
all lung cancers, and the postoperative survival of early-stage NSCLC patients remains …

Targeted therapy and immunotherapy in early-stage non-small cell lung cancer: current evidence and ongoing trials

M de Scordilli, A Michelotti, E Bertoli… - International journal of …, 2022 - mdpi.com
The scenario of neoadjuvant and adjuvant settings in non-small cell lung cancer (NSCLC) is
rapidly evolving. As already happened for the advanced disease, also early stages have …

Distribution of EML4-ALK fusion variants and clinical outcomes in patients with resected non-small cell lung cancer

H Tao, L Shi, A Zhou, H Li, F Gai, Z Huang, N Che… - Lung Cancer, 2020 - Elsevier
Objectives The molecular profiles and prognosis of anaplastic lymphoma kinase (ALK)
fusion and resectable non-small cell lung cancer (NSCLC) remain unclear. This study aimed …

[HTML][HTML] Early-stage anaplastic lymphoma kinase (ALK)-positive lung cancer: a narrative review

MF Chen, JE Chaft - Translational Lung Cancer Research, 2023 - ncbi.nlm.nih.gov
Early-stage anaplastic lymphoma kinase (ALK)-positive lung cancer: a narrative review - PMC
Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Targeted next-generation sequencing analysis for recurrence in early-stage lung adenocarcinoma

IA Kim, JY Hur, HJ Kim, JH Park, JJ Hwang… - Annals of Surgical …, 2021 - Springer
Background Despite surgical resection, early lung adenocarcinoma has a recurrence rate of
20–50%. No clear predictive markers for recurrence of early lung adenocarcinoma are …

KRAS mutations predict response and outcome in advanced lung adenocarcinoma patients receiving first-line bevacizumab and platinum-based chemotherapy

ÁK Ghimessy, Á Gellert, E Schlegl, B Hegedus, E Raso… - Cancers, 2019 - mdpi.com
Bevacizumab, combined with platinum-based chemotherapy, has been widely used in the
treatment of advanced-stage lung adenocarcinoma (LADC). Although KRAS (V-Ki-ras2 …

Neoadjuvant therapy in non-small cell lung cancer: basis, promise, and challenges

S Kalvapudi, Y Vedire, S Yendamuri, J Barbi - Frontiers in Oncology, 2023 - frontiersin.org
Introduction Survival rates for early-stage non-small cell lung cancer (NSCLC) remain poor
despite the decade-long established standard of surgical resection and systemic adjuvant …

A retrospective study of postoperative targeted therapy in ALK-positive lung cancer

B Wang, Y Song, Z Chen, X Su, X Yang, Z Wei… - Scientific Reports, 2023 - nature.com
In this study, we aim to investigate the therapeutic effect and safety of ALK inhibitor in ALK-
positive lung cancer patients. 59 patients with ALK-positive lung cancer from August 2013 to …