There is urgent need for the development of mechanistically different and less side-effect
prone antipsychotic compounds. The endocannabinoid system has been suggested to …

Schizophrenia and autism spectrum disorders (ASD) are psychiatric neurodevelopmental
disorders that cause high levels of functional disabilities. Also, the currently available …

Objective Maternal autoantibodies are a risk factor for impaired brain development in
offspring. Antibodies (ABs) against the NR1 (GluN1) subunit of the N‐methyl‐d‐aspartate …

It has been hypothesized that oxidative imbalance and alterations in nitrergic signaling play
a role in the neurobiology of schizophrenia. Preliminary evidence suggests that adjunctive …

Schizophrenia was proposed as a progressive neurodevelopmental disorder. In this regard
herein we attempted to determine progressive inflammatory and oxidative alterations …

Early-life challenges, particularly infections and stress, are related to neuropsychiatric
disorders such as autism and schizophrenia. Here, we conducted a wide range of …

Evidence suggest that prenatal immune system disturbance contributes largely to the
pathophysiology of neuropsychiatric disorders. We investigated if maternal immune …

Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been
reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We …

Oxidative stress has important implications in schizophrenia. Alpha-lipoic acid (ALA) is a
natural antioxidant synthesized in human tissues with clinical uses. We studied the effect of …

Schizophrenia is considered a debilitating neurodevelopmental psychiatric disorder and its
pharmacotherapy remains problematic without recent major advances. The development of …