First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial

P Baas, A Scherpereel, AK Nowak, N Fujimoto… - The Lancet, 2021 - thelancet.com
Background Approved systemic treatments for malignant pleural mesothelioma (MPM) have
been limited to chemotherapy regimens that have moderate survival benefit with poor …

Clinical utility of diagnostic biomarkers in malignant pleural mesothelioma: A systematic review and meta-analysis

E Schillebeeckx, JP van Meerbeeck… - European Respiratory …, 2021 - Eur Respiratory Soc
Malignant pleural mesothelioma (MPM) is characterised by late-stage diagnosis and poor
prognosis. Currently, no screening tool is advocated and diagnosis is based on invasive …

[HTML][HTML] Update on biology and management of mesothelioma

R Asciak, V George, NM Rahman - European Respiratory …, 2021 - Eur Respiratory Soc
Malignant pleural mesothelioma is an aggressive, incurable cancer that is usually caused by
asbestos exposure several decades before symptoms arise. Despite widespread prohibition …

Comparison of 3 randomized clinical trials of frontline therapies for malignant pleural mesothelioma

T Meirson, F Pentimalli, F Cerza, G Baglio… - JAMA Network …, 2022 - jamanetwork.com
Importance Some recently proposed frontline therapies for malignant pleural mesothelioma
(MPM) are very costly, yet their impact on quality of life and overall survival of these patients …

Evidence‐based diagnostic performance of novel biomarkers for the diagnosis of malignant mesothelioma in effusion cytology

I Girolami, E Lucenteforte, A Eccher… - Cancer …, 2022 - Wiley Online Library
Cytology effusions are often the only material available for diagnosing malignant pleural
mesothelioma (MPM). However, the cytomorphological features alone are not always …

Malignant pleural mesothelioma: recent developments

K Sinn, B Mosleh, MA Hoda - Current Opinion in Oncology, 2021 - journals.lww.com
Malignant pleural mesothelioma: recent developments : Current Opinion in Oncology Malignant
pleural mesothelioma: recent developments : Current Opinion in Oncology Log in or Register …

[HTML][HTML] Rapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum

D Yonar, M Severcan, R Gurbanov, A Sandal… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Malignant pleural mesothelioma (MPM), an aggressive cancer associated with exposure to
fibrous minerals, can only be diagnosed in the advanced stage because its early symptoms …

[HTML][HTML] CSF1/CSF1R axis blockade limits mesothelioma and enhances efficiency of anti-PDL1 immunotherapy

SF Magkouta, PC Vaitsi, AG Pappas, M Iliopoulou… - Cancers, 2021 - mdpi.com
Simple Summary CSF1/CSF1R signaling mediates tumor-associated macrophages
recruitment and M2 polarization. M2 TAMs are dominant immune populations infiltrating …

Diagnostic mesothelioma biomarkers in effusion cytology

A Eccher, I Girolami, E Lucenteforte… - Cancer …, 2021 - Wiley Online Library
Malignant mesothelioma is a rare malignancy with a poor prognosis whose development is
related to asbestos fiber exposure. An increasing role of genetic predisposition has been …

[HTML][HTML] Multimodal therapy of epithelioid pleural mesothelioma: improved survival by changing the surgical treatment approach

LV Klotz, H Hoffmann, R Shah, F Eichhorn… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background The exact role and type of surgery for malignant pleural mesothelioma (MPM)
remains controversial. This study aimed at analyzing a 20-year single center perioperative …