Background: Neonatal hypoxic ischemic encephalopathy (HIE) remains a significant cause
of mortality and morbidity worldwide. Cerebral near infrared spectroscopy (NIRS) can …

Cerebrovascular reactivity defines the ability of the cerebral vasculature to regulate its
resistance in response to both local and systemic factors to ensure an adequate cerebral …

Neonatal encephalopathy due to a hypoxic-ischemic event is commonly associated with
cardiac dysfunction and acute pulmonary hypertension; both therapeutic hypothermia and …

Post-hemorrhagic ventricular dilatation (PHVD) is characterized by a build-up of cerebral
spinal fluid (CSF) in the ventricles, which increases intracranial pressure and compresses …

In this review, we describe the near-infrared spectroscopy (NIRS) technology and its clinical
use in high-risk neonates in critical care settings. We searched databases (eg, PubMed …

The understanding of molecular biology in neurocritical care (NCC) is expanding rapidly
and recognizing the important contribution of neuroinflammation, specifically changes in …

Neonatal encephalopathy following hypoxia-ischaemia occurs in 1-3 per 1000 term births in
the UK. Despite therapeutic hypothermia only around 30% survive with normal …

Hypoxic ischemic encephalopathy (HIE) is associated with lung parenchymal disease, acute
pulmonary hypertension, cardiac dysfunction and adrenal insufficiency. Treatment with …