Mass effect of injected dose in small rodent imaging by SPECT and PET

MP Kung, HF Kung - Nuclear medicine and biology, 2005 - Elsevier
This paper discusses the effect of mass (chemical quantity) of injected dose on positron
emission tomography (PET) and single-photon emission computed tomography (SPECT) …

Quantitative rodent brain receptor imaging

K Herfert, JG Mannheim, L Kuebler, S Marciano… - Molecular Imaging and …, 2020 - Springer
Positron emission tomography (PET) is a non-invasive imaging technology employed to
describe metabolic, physiological, and biochemical processes in vivo. These include …

Serial microPET measures of the metabolic reaction to a microdialysis probe implant

WK Schiffer, MM Mirrione, A Biegon, DL Alexoff… - Journal of neuroscience …, 2006 - Elsevier
Despite the widespread use of chronic brain implants in experimental and clinical settings,
the effects of these long-term procedures on brain metabolism and receptor expression …

Therapeutic doses of amphetamine or methylphenidate differentially increase synaptic and extracellular dopamine

WK Schiffer, ND Volkow, JS Fowler, DL Alexoff… - Synapse, 2006 - Wiley Online Library
Methylphenidate (MP) and amphetamine (AMP) are first‐line treatments for attention‐deficit
hyperactivity disorder. Although both drugs have similar therapeutic potencies, the …

Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease

JA Rodríguez-Gómez, JQ Lu, I Velasco, S Rivera… - Stem …, 2007 - academic.oup.com
The derivation of dopamine neurons is one of the best examples of the clinical potential of
embryonic stem (ES) cells, but the long-term function of the grafted neurons has not been …

EANM guideline for harmonisation on molar activity or specific activity of radiopharmaceuticals: impact on safety and imaging quality

G Luurtsema, V Pichler, S Bongarzone… - EJNMMI …, 2021 - Springer
This guideline on molar activity (A m) and specific activity (A s) focusses on small molecules,
peptides and macromolecules radiolabelled for diagnostic and therapeutic applications. In …

[HTML][HTML] Resveratrol promotes axonal regeneration after spinal cord injury through activating Wnt/β-catenin signaling pathway

Z Xiang, S Zhang, X Yao, L Xu, J Hu, C Yin… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: Spinal cord injury (SCI) is characterized by autonomic dysreflexia, chronic
pain, sensory and motor deficits. Resveratrol has shown potential neuroprotective function in …

Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior

MM Mirrione, D Schulz, KAB Lapidus… - Frontiers in human …, 2014 - frontiersin.org
Uncontrollable stress can have a profound effect on an organism's ability to respond
effectively to future stressful situations. Behavior subsequent to uncontrollable stress can …

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

PK Thanos, NB Taintor, SN Rivera… - Alcoholism: Clinical …, 2004 - Wiley Online Library
Background: Transient overexpression of the dopamine D2 receptor (DRD2) gene in the
nucleus accumbens (NAc) using an adenoviral vector has been associated with a significant …

A novel approach for imaging brain–behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen …

MM Mirrione, WK Schiffer, JS Fowler, DL Alexoff… - Neuroimage, 2007 - Elsevier
Medically refractory seizures cause inflammation and neurodegeneration. Seizure initiation
thresholds have been linked in mice to the serine protease tissue plasminogen activator …