Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Owing to its ability to depict the pathologic features of multiple sclerosis (MS) in exquisite
detail, conventional magnetic resonance (MR) imaging has become an established tool in …

Axonal degeneration is an initial key step in traumatic and neurodegenerative CNS
disorders. We established a unique in vivo epifluorescence imaging paradigm to …

Multiple sclerosis (MS) is an inflammatory‐demyelinating and neurodegenerative disease of
the central nervous system (CNS) and the most frequent cause of non‐traumatic disability in …

Recent years have witnessed impressive advances in the use of magnetic resonance
imaging (MRI) for the assessment of patients with multiple sclerosis (MS). Complementary to …

Recently, remarkable success has been demonstrated in using MR diffusion tensor imaging
(DTI) to characterize white matter. Water diffusion in complex biological tissue microstructure …

Previous studies suggest that thalamic degeneration is prominent in multiple sclerosis (MS)
and even in pre-MS patients presenting with a clinically isolated syndrome (CIS). However …

Abstract From the Section Editor: The next two installments in the JNO “Disease of the Year:
Multiple Sclerosis” series focus on lessons that can be learned form the afferent visual …

The retinogeniculate visual pathway (RGVP) conveys visual information from the retina to
the lateral geniculate nucleus. The RGVP has four subdivisions, including two decussating …

Objective: Diffusion tensor imaging (DTI) quantifies Brownian motion of water within tissue.
The goal of this study was to test whether, following a remote episode of optic neuritis (ON) …