[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis
M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
Self-assembling nucleic acid nanostructures functionalized with aptamers
A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
Advancement of the emerging field of RNA nanotechnology
The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …
information and translation of the genetic code into proteins, DNA holds great promise as a …
The emerging field of RNA nanotechnology
P Guo - Nature nanotechnology, 2010 - nature.com
Like DNA, RNA can be designed and manipulated to produce a variety of different
nanostructures. Moreover, RNA has a flexible structure and possesses catalytic functions …
nanostructures. Moreover, RNA has a flexible structure and possesses catalytic functions …
Nanomaterials based on DNA
NC Seeman - Annual review of biochemistry, 2010 - annualreviews.org
The combination of synthetic stable branched DNA and sticky-ended cohesion has led to the
development of structural DNA nanotechnology over the past 30 years. The basis of this …
development of structural DNA nanotechnology over the past 30 years. The basis of this …
A single-stranded architecture for cotranscriptional folding of RNA nanostructures
Artificial DNA and RNA structures have been used as scaffolds for a variety of nanoscale
devices. In comparison to DNA structures, RNA structures have been limited in size, but they …
devices. In comparison to DNA structures, RNA structures have been limited in size, but they …
RNA self-assembly and RNA nanotechnology
WW Grabow, L Jaeger - Accounts of chemical research, 2014 - ACS Publications
Conspectus Nanotechnology's central goal involves the direct control of matter at the
molecular nanometer scale to build nanofactories, nanomachines, and other devices for …
molecular nanometer scale to build nanofactories, nanomachines, and other devices for …
In vitro assembly of cubic RNA-based scaffolds designed in silico
The organization of biological materials into versatile three-dimensional assemblies could
be used to build multifunctional therapeutic scaffolds for use in nanomedicine. Here, we …
be used to build multifunctional therapeutic scaffolds for use in nanomedicine. Here, we …
Stable RNA nanoparticles as potential new generation drugs for cancer therapy
Y Shu, F Pi, A Sharma, M Rajabi, F Haque… - Advanced drug delivery …, 2014 - Elsevier
Human genome sequencing revealed that only~ 1.5% of the DNA sequence coded for
proteins. More and more evidence has uncovered that a substantial part of the 98.5% so …
proteins. More and more evidence has uncovered that a substantial part of the 98.5% so …