Anticancer property of ginsenoside Rh2 from ginseng
X Li, S Chu, M Lin, Y Gao, Y Liu, S Yang, X Zhou… - European Journal of …, 2020 - Elsevier
Ginseng has been used as a well-known traditional Chinese medicine since ancient times.
Ginsenosides as its main active constituents possess a broad scope of pharmacological …
Ginsenosides as its main active constituents possess a broad scope of pharmacological …
VDAC1, mitochondrial dysfunction, and Alzheimer's disease
V Shoshan-Barmatz, E Nahon-Crystal… - Pharmacological …, 2018 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disorder. Although an
accumulation of brain amyloid-β (Aβ) peptide and hyperphosphorylated tau protein have …
accumulation of brain amyloid-β (Aβ) peptide and hyperphosphorylated tau protein have …
The amphiphilic nature of saponins and their effects on artificial and biological membranes and potential consequences for red blood and cancer cells
JH Lorent, J Quetin-Leclercq… - Organic & biomolecular …, 2014 - pubs.rsc.org
Saponins, amphiphiles of natural origin with numerous biological activities, are widely used
in the cosmetic and pharmaceutical industry. Some saponins exhibit relatively selective …
in the cosmetic and pharmaceutical industry. Some saponins exhibit relatively selective …
Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies
H Wang, Y Zheng, Q Sun, Z Zhang, M Zhao… - Journal of …, 2021 - Springer
Ginsenosides, the main components isolated from Panax ginseng, can play a therapeutic
role by inducing tumor cell apoptosis and reducing proliferation, invasion, metastasis; by …
role by inducing tumor cell apoptosis and reducing proliferation, invasion, metastasis; by …
Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure–Activity Relationships, and Molecular Mechanisms of Action
Conventional chemotherapeutic agents are often toxic not only to tumor cells but also to
normal cells, limiting their therapeutic use in the clinic. Novel natural product anticancer …
normal cells, limiting their therapeutic use in the clinic. Novel natural product anticancer …
Saponins from Chinese medicines as anticancer agents
Saponins are glycosides with triterpenoid or spirostane aglycones that demonstrate various
pharmacological effects against mammalian diseases. To promote the research and …
pharmacological effects against mammalian diseases. To promote the research and …
Plasma membrane lipid domains as platforms for vesicle biogenesis and shedding?
H Pollet, L Conrard, AS Cloos, D Tyteca - Biomolecules, 2018 - mdpi.com
Extracellular vesicles (EVs) contribute to several pathophysiological processes and appear
as emerging targets for disease diagnosis and therapy. However, successful translation from …
as emerging targets for disease diagnosis and therapy. However, successful translation from …
Ginsenoside 20 (S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells
Ethnopharmacological relevance Panax ginseng is one of the most well-known medicinal
herbs in Korea and China, which has been used for treatment and prevention of cancer …
herbs in Korea and China, which has been used for treatment and prevention of cancer …
New generation of drug delivery systems based on ginsenoside Rh2-, Lysine-and Arginine-treated highly porous graphene for improving anticancer activity
In this study, Rh2–treated graphene oxide (GO-Rh2), lysine-treated highly porous graphene
(Gr-Lys), arginine-treated Gr (Gr-Arg), Rh2–treated Gr-Lys (Gr-Lys-Rh2) and Rh2–treated Gr …
(Gr-Lys), arginine-treated Gr (Gr-Arg), Rh2–treated Gr-Lys (Gr-Lys-Rh2) and Rh2–treated Gr …
Membrane rafts as a novel target in cancer therapy
A Hryniewicz-Jankowska, K Augoff… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Membrane rafts are distinct plasma membrane microdomains that are enriched in
sphingolipids and cholesterol. They organize receptors and their downstream molecules …
sphingolipids and cholesterol. They organize receptors and their downstream molecules …