[HTML][HTML] Transcriptomic and Genomic Approaches for Unravelling Candida albicans Biofilm Formation and Drug Resistance—An Update

PP Chong, VK Chin, WF Wong, P Madhavan, VC Yong… - Genes, 2018 - mdpi.com
Candida albicans is an opportunistic fungal pathogen, which causes a plethora of
superficial, as well as invasive, infections in humans. The ability of this fungus in switching …

Heterogeneity among isolates reveals that fitness in low oxygen correlates with Aspergillus fumigatus virulence

CH Kowalski, SR Beattie, KK Fuller, EA McGurk… - MBio, 2016 - Am Soc Microbiol
Previous work has shown that environmental and clinical isolates of Aspergillus fumigatus
represent a diverse population that occupies a variety of niches, has extensive genetic …

[HTML][HTML] Cryptococcus neoformans and Other Opportunistic Cryptococcus Species in Pigeon Dropping in Saudi Arabia: Identification and Characterization by DNA …

B Sirag, ES Khidir, M Dumyati, B Sindi… - Frontiers in …, 2021 - frontiersin.org
The prevalent variants of Cryptococcus neoformans, and other Cryptococcus species in
pigeon excreta in Western Region of Saudi Arabia were studied. Ninety pigeon dropping …

Comparative typing analyses of clinical and environmental strains of the Cryptococcus neoformans/Cryptococcus gattii species complex from Ivory Coast

FK Kassi, V Bellet, P Drakulovski… - Journal of Medical …, 2018 - microbiologyresearch.org
Purpose. The aim of this study was to assess the biotope of the Cryptococcus neoformans/
Cryptococcus gattii species complex from Ivory Coast, and clarify the possible …

It's not all about us: evolution and maintenance of Cryptococcus virulence requires selection outside the human host

AC Gerstein, K Nielsen - Yeast, 2017 - Wiley Online Library
Cryptococcus is predominantly an AIDS‐related pathogen that causes significant morbidity
and mortality in immunocompromised patients. Research studies have historically focused …

Toward a clinical antifungal peptoid: Investigations into the therapeutic potential of AEC5

SK Spicer, A Subramani, AL Aguila, RM Green… - …, 2019 - Wiley Online Library
Cryptococcus neoformans is a fungal pathogen that causes cryptococcal meningitis in
immunocompromised individuals. Existing antifungal treatment plans have high mammalian …

[HTML][HTML] Transcriptional Profiles Elucidate Differential Host Responses to Infection with Cryptococcus neoformans and Cryptococcus gattii

ZE Holcomb, JM Steinbrink, AK Zaas, M Betancourt… - Journal of Fungi, 2022 - mdpi.com
Many aspects of the host response to invasive cryptococcal infections remain poorly
understood. In order to explore the pathobiology of infection with common clinical strains, we …

Improved potency and reduced toxicity of the antifungal peptoid AEC5 through submonomer modification

MP Middleton, SA Armstrong, KL Bicker - Bioorganic & medicinal chemistry …, 2018 - Elsevier
As proteolytically stable peptidomimetics, peptoids could serve as antifungal agents to
supplement a therapeutic field wrought with toxicity issues. We report the improvement of an …

[HTML][HTML] Lung–infiltrating T helper 17 cells as the major source of interleukin-17A production during pulmonary Cryptococcus neoformans infection

E Movahed, YY Cheok, GMY Tan, CYQ Lee… - BMC immunology, 2018 - Springer
Background IL-17A has emerged as a key player in the pathologies of inflammation,
autoimmune disease, and immunity to microbes since its discovery two decades ago. In this …

[HTML][HTML] Prevalence, Genetic Structure and Antifungal Susceptibility of the Cryptococcus neoformans/C. gattii Species Complex Strains Collected from the Arboreal …

M Florek, A Korzeniowska-Kowal, A Wzorek… - Pathogens, 2021 - mdpi.com
Fungi belonging to the Cryptococcus neoformans/C. gattii species complex (CNGSC) are
etiological agents of serious and not infrequently fatal infections in both humans and …