BACKGROUND According to the Developmental Origins of Health and Disease (DOHaD)
hypothesis, environmental changes taking place during early maturational periods may alter …

Embryonic and foetal development are critical periods of development in which several
environmental cues determine health and disease in adulthood. Maternal conditions and an …

Key points Maternal high‐fat diet consumption predisposes to metabolic dysfunction in male
and female offspring at young adulthood. Maternal obesity programs non‐alcoholic fatty liver …

It is well established that early life environmental signals, including nutrition, set the stage for
long-term health and disease risk–effects that span multiple generations. This relationship …

Cholesterol is essential for mammalian cell functions and integrity. It is an important
structural component maintaining the permeability and fluidity of the cell membrane. The …

Key points Maternal obesity predisposes to metabolic dysfunction in male and female
offspring Maternal high‐fat diet consumption prior to and throughout pregnancy and …

Obesity is an increasing global health epidemic that affects all ages, including women of
reproductive age. During pregnancy, maternal obesity is associated with adverse pregnancy …

The prevalence of obesity in women of reproductive age is increasing in developed and
developing countries around the world. Human and animal studies indicate that maternal …

Parental nutrition can impact the health of future generations, programming the offspring for
the development of diseases. The developing germ cells of the offspring could be damaged …

Maternal exposure to the high‐fat diet (HFD) during gestation or lactation can be harmful to
both a mother and offspring. The aim of this systematic review was to identify and evaluate …