Sperm DNA integrity is essential for the accurate transmission of genetic information. It has a
highly compact and complex structure and is capable of decondensation—features that must …

Twenty-five years ago the first human, Louise Brown, was conceived outside the body, and
this event created a new milestone in the history of mankind and the concept of human in …

BACKGROUND: Standard sperm characteristics are poor predictors of the outcome of IVF
treatments. On the contrary, sperm genome quality has been emphasized for several years …

Infertility rates and the number of couples seeking fertility care have increased worldwide
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …

Among infertile couples, 25% involve both male and female factors, while male factor alone
accounts for another 25% due to oligo-, astheno-, teratozoospermia, a combination of the …

OBJECTIVE: To examine sperm DNA fragmentation in semen used for assisted reproduction
procedures to establish this factor's prognostic role in fertilization rate, embryo development …

Subjects increasing sperm DNA fragmentation (sDF) during Density Gradient Centrifugation
(DGC), a common sperm selection procedure in Assisted Reproduction Techniques (ARTs) …

Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

OBJECTIVE: To evaluate sperm DNA fragmentation and semen parameters to diagnose
male factor infertility and predict pregnancy after IVF. DESIGN: Prospective study. SETTING …

Background The initial step in the diagnostic investigation of male infertility has been
traditionally based on the conventional seminal profile. However, there are significant …