Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …

Many patients after mild or moderate TBI suffer long-term sequelae and should be
considered a major target for translational research. Treatments that improve outcome in …

Traumatic brain injury (TBI) causes 10–20% of structural epilepsies and 5% of all epilepsies.
The lack of prognostic biomarkers for post-traumatic epilepsy (PTE) is a major obstacle to …

History of traumatic brain injury (TBI) represents a significant risk factor for development of
dementia and neurodegenerative disorders in later life. While histopathological sequelae …

Background Subconcussive blast exposure during military training has been the subject of
both anecdotal concerns and reports in the medical literature, but prior studies have often …

Pre-analytical factors have a significant influence on circulating microRNA (miRNA) profiling.
The aim of this study was a comprehensive assessment of the impact of the anticoagulant …

Extracellular vesicles (EVs) are small vesicles involved in intercellular communication. Data
is emerging that EVs and their cargo have potential as diagnostic biomarkers and treatments …

Death by mechanical asphyxia is one of the most difficult conclusions to make in forensic
science, especially in corpses displaying slight or no trauma to the surface of the body …

Repetitive head impacts (RHI) are common in youth athletes participating in contact sports.
RHI differ from concussions; they are considered hits to the head that usually do not result in …

Determining the cause of death is one of the main goals of forensic pathology. However,
conditions can occur in which common approaches—external inspection, autopsy, histology …