Biological activities of [1,2,4]triazolo[1,5-a]pyrimidines and analogs

S Pinheiro, EMC Pinheiro, EMF Muri… - Medicinal Chemistry …, 2020 - Springer
Abstract The [1, 2, 4] triazolo [1, 5-a] pyrimidines (TPs) comprise an important class of non-
naturally occurring small molecules that aroused the interest of researches. This scaffold is …

[图书][B] Medicinal plants of the world, volume 3: Chemical constituents, traditional and modern medicinal uses

IA Ross - 2007 - books.google.com
An extraordinary compendium of information on herbal medicine, Medicinal Plants of the
World, Volume 3 comprehensively documents the medicinal value of 16 major plant species …

[HTML][HTML] Traditional uses, phytochemistry, pharmacology and toxicity of Arisaema (Areaceae): a review

H Ali, U Yaqoob - Bulletin of the National Research Centre, 2021 - Springer
Abstract Background The genus Arisaema (Areaceae), popularly known as cobra lilies and
jack in pulpit is mainly found in temperate to tropical areas of all continents except South …

Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo [3, 2-a] pyrimidines

NS El-Sayed, ER El-Bendary, SM El-Ashry… - European journal of …, 2011 - Elsevier
New series of sulfonamide derivatives of [1, 3, 4] thiadiazolo [3, 2-a] pyrimidine were
synthesized and investigated as antitumor agents. Some of the newly prepared compounds …

Synthesis, structures, DNA-binding and anticancer activities of some copper (I)-phosphine complexes

KH Mashat, BA Babgi, MA Hussien, MN Arshad… - Polyhedron, 2019 - Elsevier
Copper (I) complexes with a phenanthroline-phosphine set of ligands were synthesized by
refluxing methanolic solutions of CuBr 2 with at least a four fold molar excess of the …

Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling …

AM Alaa - European journal of medicinal chemistry, 2007 - Elsevier
Versatile method has been developed for synthesis of N-substituted imides. Thus, acid
anhydrides, imides and dicarboxylic acids were successfully subjected to dehydrative …

Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents

NS El-Gohary, MI Shaaban - European journal of medicinal chemistry, 2017 - Elsevier
New benzimidazole derivatives were synthesized and assessed for antimicrobial efficacy
toward Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans and …

Mechanistic evaluation of new plant-derived compounds that inhibit HIV-1 reverse transcriptase

T Pengsuparp, L Cai, H Constant… - Journal of natural …, 1995 - ACS Publications
DNA polymerase activity of human immunodeficiency virus-1 reverse transcriptase (HTV-1
RT), with 50% inhibitory doses (IC,„values) of 43, 3.7, and 24 µ, respectively. They were not …

A colorimetric microassay for the detection of agents that interact with DNA

NS Burres, A Frigo, RR Rasmussen… - Journal of natural …, 1992 - ACS Publications
A simple microtiter assay for the detection of compounds that bind DNA is described. Agents
that displace methyl green from DNA are detected spectrophotometrically by a decrease in …

Screening of Panamanian medicinal plants for brine shrimp toxicity, crown gall tumor inhibition, cytotoxicity and DNA intercalation

MP Gupta, A Monge, GA Karikas… - International Journal …, 1996 - Taylor & Francis
Crude extracts from 20 Panamanian plants used in traditional medicine have been screened
for brine shrimp toxicity, tumor inhibition, DNA-intercalation and cytotoxicity tests in a …