Trends in insulin resistance: insights into mechanisms and therapeutic strategy
M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
The expanding role of pyridine and dihydropyridine scaffolds in drug design
Y Ling, ZY Hao, D Liang, CL Zhang… - Drug design …, 2021 - Taylor & Francis
Pyridine-based ring systems are one of the most extensively used heterocycles in the field of
drug design, primarily due to their profound effect on pharmacological activity, which has led …
drug design, primarily due to their profound effect on pharmacological activity, which has led …
Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction
Heavy metal-induced cellular and organismal toxicity have become a major health concern
in biomedical science. Indiscriminate use of heavy metals in different sectors, such as …
in biomedical science. Indiscriminate use of heavy metals in different sectors, such as …
Long-lived emissive probes for time-resolved photoluminescence bioimaging and biosensing
KY Zhang, Q Yu, H Wei, S Liu, Q Zhao… - Chemical …, 2018 - ACS Publications
In this Review article, we systematically summarize the design and applications of various
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …
Inorganic biomaterials for regenerative medicine
AM Brokesh, AK Gaharwar - ACS applied materials & interfaces, 2020 - ACS Publications
Regenerative medicine leverages the innate potential of the human body to efficiently repair
and regenerate damaged tissues using engineered biomaterials. By designing responsive …
and regenerate damaged tissues using engineered biomaterials. By designing responsive …
Contaminant-induced oxidative stress in fish: a mechanistic approach
VI Lushchak - Fish physiology and biochemistry, 2016 - Springer
The presence of reactive oxygen species (ROS) in living organisms was described more
than 60 years ago and virtually immediately it was suggested that ROS were involved in …
than 60 years ago and virtually immediately it was suggested that ROS were involved in …
[HTML][HTML] New evidence against chromium as an essential trace element
JB Vincent - The Journal of nutrition, 2017 - Elsevier
Nearly 60 y ago, chromium, as the trivalent ion, was proposed to be an essential element,
but the results of new studies indicate that chromium currently can only be considered …
but the results of new studies indicate that chromium currently can only be considered …
[HTML][HTML] Disease-associated metabolic pathways affected by heavy metals and metalloid
Increased exposure to environmental heavy metals and metalloids and their associated
toxicities has become a major threat to human health. Hence, the association of these …
toxicities has become a major threat to human health. Hence, the association of these …
[HTML][HTML] ESPEN micronutrient guideline
MM Berger, A Shenkin, A Schweinlin, K Amrein… - Clinical Nutrition, 2022 - Elsevier
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …
essential for human metabolism. Recent research has shown the importance of MNs in …
Oxidative stress and metal carcinogenesis
JC Lee, YO Son, P Pratheeshkumar, X Shi - Free radical biology and …, 2012 - Elsevier
Occupational and environmental exposures to metals are closely associated with an
increased risk of various cancers. Although carcinogenesis caused by metals has been …
increased risk of various cancers. Although carcinogenesis caused by metals has been …