Triple negative breast cancer (TNBC) is most aggressive subtype of breast cancers with high
probability of metastasis as well as lack of specific targets and targeted therapeutics. TNBC …

Anti-HER2 treatment for HER2-positive breast cancer has changed the natural biology of
this disease. This Series article reviews the main achievements so far in the treatment of …

Breast cancer is a kind of malignant tumor that mainly appears in the inner lining of milk
ducts, epithelial tissues, or lobules with different degrees of spread, invasiveness, and …

The clinical manifestation of metastasis in a vital organ is the final stage of cancer
progression and the main culprit of cancer-related mortality. Once established, metastasis is …

Results A total of 243,896 patients, including 226,451 cases in control groups were
identified. Bone metastasis was found in 8848 cases, compared with 1,000 brain metastasis …

Distant metastasis accounts for the vast majority of deaths in patients with cancer. Breast
cancer exhibits a distinct metastatic pattern commonly involving bone, liver, lung, and brain …

Because of improvements in the treatment of patients with metastatic breast cancer, the
development of brain metastases (BM) has become a major limitation of life expectancy and …

This comprehensive review provides information on epidemiology, size, grade, cerebral
localization, clinical symptoms, treatments, and factors associated with longer survival in …

Many cancer types metastasize to bone. This propensity may be a product of genetic traits of
the primary tumour in some cancers. Upon arrival, cancer cells establish interactions with …

To investigate the significance and impact of molecular subtyping stratification on metastatic
breast cancer patients, we identified 159,344 female breast cancer patients in the …