[HTML][HTML] Therapeutic advances of miRNAs: A preclinical and clinical update
C Chakraborty, AR Sharma, G Sharma… - Journal of advanced …, 2021 - Elsevier
Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …
[HTML][HTML] MicroRNA delivery through nanoparticles
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
[HTML][HTML] Recent advances in miRNA delivery systems
I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
MicroRNAs (miRNAs) represent a family of short non-coding regulatory RNA molecules that
are produced in a tissue and time-specific manner to orchestrate gene expression post …
are produced in a tissue and time-specific manner to orchestrate gene expression post …
[HTML][HTML] siRNA versus miRNA as therapeutics for gene silencing
JKW Lam, MYT Chow, Y Zhang, SWS Leung - Molecular Therapy-Nucleic …, 2015 - cell.com
Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …
Recent progress in development of siRNA delivery vehicles for cancer therapy
Recent progress in RNA biology has broadened the scope of therapeutic targets of RNA
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
[HTML][HTML] Recent progress in microRNA-based delivery systems for the treatment of human disease
Y Fu, J Chen, Z Huang - ExRNA, 2019 - Springer
MicroRNAs (miRNAs) are naturally occurring, small non-coding RNAs that mediate
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …
Exosome-mediated microRNA-497 delivery for anti-cancer therapy in a microfluidic 3D lung cancer model
Non-small cell lung cancer (NSCLC) is one of the leading causes of death from cancer
worldwide. The delivery and controlled regulation of miRNAs via exosomes is known as a …
worldwide. The delivery and controlled regulation of miRNAs via exosomes is known as a …
[HTML][HTML] Going beyond the liver: progress and challenges of targeted delivery of siRNA therapeutics
C Lorenzer, M Dirin, AM Winkler, V Baumann… - Journal of Controlled …, 2015 - Elsevier
Therapeutic gene silencing promises significant progress in pharmacotherapy, including
considerable expansion of the druggable target space and the possibility for treating orphan …
considerable expansion of the druggable target space and the possibility for treating orphan …
Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo
P Zhupanyn, A Ewe, T Büch, A Malek… - Journal of Controlled …, 2020 - Elsevier
Extracellular vesicles (ECVs) are secreted cell-derived membrane particles involved in
intercellular signaling and cell-cell communication. By transporting various bio …
intercellular signaling and cell-cell communication. By transporting various bio …
Innovative approaches in transforming microRNAs into therapeutic tools
AFA Samad, MF Kamaroddin - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
MicroRNA (miRNA) is regarded as a prominent genetic regulator, as it can fine‐tune an
entire biological pathway by targeting multiple target genes. This characteristic makes …
entire biological pathway by targeting multiple target genes. This characteristic makes …