[HTML][HTML] Natural therapeutics and nutraceuticals for lung diseases: traditional significance, phytochemistry, and pharmacology
Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …
Preparation and evaluation of chitosan/PVA based hydrogel films loaded with honey for wound healing application
In the present study, chitosan/polyvinyl alcohol (PVA)-based honey hydrogel films were
developed for potential wound healing application. The hydrogel films were developed by a …
developed for potential wound healing application. The hydrogel films were developed by a …
[HTML][HTML] Modern drug discovery applications for the identification of novel candidates for COVID-19 infections
In early December 2019, a large pneumonia epidemic occurred in Wuhan, China. The World
Health Organization is concerned about the outbreak of another coronavirus with the …
Health Organization is concerned about the outbreak of another coronavirus with the …
Identification of novel peptide inhibitors for the KRas-G12C variant to prevent oncogenic signaling
Kirsten rat sarcoma viral oncogene homolog (KRas) activating mutations are common in
solid tumors, accounting for 90%, 45%, and 35% of pancreatic, colorectal, and lung cancers …
solid tumors, accounting for 90%, 45%, and 35% of pancreatic, colorectal, and lung cancers …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
[HTML][HTML] Virtual screening and molecular dynamics simulation analysis of Forsythoside A as a plant-derived inhibitor of SARS-CoV-2 3CLpro
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a more severe strain of
coronavirus (CoV) that was first emerged in China in 2019. Available antiviral drugs could …
coronavirus (CoV) that was first emerged in China in 2019. Available antiviral drugs could …
In vitro and in silico characterization of curcumin-loaded chitosan–PVA hydrogels: antimicrobial and potential wound healing activity
Curcumin has been used in traditional medicine forages. The present study aimed to
develop a curcumin-based hydrogel system and assess its antimicrobial potential and …
develop a curcumin-based hydrogel system and assess its antimicrobial potential and …
Design and synthesis of new flavonols as dual ɑ-amylase and ɑ-glucosidase inhibitors: structure-activity relationship, drug-likeness, in vitro and in silico studies
In this study, a library of new intriguing flavonol derivatives (1–17) was designed and
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …
[HTML][HTML] Predicting Meridian in Chinese traditional medicine using machine learning approaches
Plant-derived nature products, known as herb formulas, have been commonly used in
Traditional Chinese Medicine (TCM) for disease prevention and treatment. The herbs have …
Traditional Chinese Medicine (TCM) for disease prevention and treatment. The herbs have …
[HTML][HTML] α-Glucosidase inhibitory activity of cannabidiol, tetrahydrocannabinol and standardized cannabinoid extracts from Cannabis sativa
Two major cannabinoids of cannabis, namely cannabidiol (CBD) and tetrahydrocannabinol
(THC) have been reportedly used as alternative medicine for diabetes treatment in both pre …
(THC) have been reportedly used as alternative medicine for diabetes treatment in both pre …