Toward a fully resolved fungal tree of life
In this review, we discuss the current status and future challenges for fully elucidating the
fungal tree of life. In the last 15 years, advances in genomic technologies have …
fungal tree of life. In the last 15 years, advances in genomic technologies have …
Combatting the evolution of antifungal resistance in Cryptococcus neoformans
A Bermas, J Geddes‐McAlister - Molecular microbiology, 2020 - Wiley Online Library
Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
Fungal species concepts in the genomics era
J Xu - Genome, 2020 - cdnsciencepub.com
The 140 000 or so fungal species reported so far are heterogeneously defined based on
varying criteria such as morphological, physiological, mating, and (or) molecular features …
varying criteria such as morphological, physiological, mating, and (or) molecular features …
Assessing global fungal threats to humans
J Xu - mLife, 2022 - Wiley Online Library
Fungi are an integral part of the earth's biosphere. They are broadly distributed in all
continents and ecosystems and play a diversity of roles. Here, I review our current …
continents and ecosystems and play a diversity of roles. Here, I review our current …
[HTML][HTML] Genomic evidence for a hybrid origin of the yeast opportunistic pathogen Candida albicans
V Mixão, T Gabaldón - BMC biology, 2020 - Springer
Background Opportunistic yeast pathogens of the genus Candida are an important medical
problem. Candida albicans, the most prevalent Candida species, is a natural commensal of …
problem. Candida albicans, the most prevalent Candida species, is a natural commensal of …
Clonality, inbreeding, and hybridization in two extremotolerant black yeasts
C Gostinčar, X Sun, A Černoša, C Fang… - …, 2022 - academic.oup.com
Background The great diversity of lifestyles and survival strategies observed in fungi is
reflected in the many ways in which they reproduce and recombine. Although a complete …
reflected in the many ways in which they reproduce and recombine. Although a complete …
A conceptual framework for nomenclatural stability and validity of medically important fungi: a proposed global consensus guideline for fungal name changes …
The rapid pace of name changes of medically important fungi is creating challenges for
clinical laboratories and clinicians involved in patient care. We describe two sources of …
clinical laboratories and clinicians involved in patient care. We describe two sources of …
Microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid genome diversification
GM Matos, MD Lewis, C Talavera-López, M Yeo… - Elife, 2022 - elifesciences.org
Protozoa and fungi are known to have extraordinarily diverse mechanisms of genetic
exchange. However, the presence and epidemiological relevance of genetic exchange in …
exchange. However, the presence and epidemiological relevance of genetic exchange in …
[HTML][HTML] Global Analyses of Multi-Locus Sequence Typing Data Reveal Geographic Differentiation, Hybridization, and Recombination in the Cryptococcus gattii …
M Hitchcock, J Xu - Journal of Fungi, 2023 - mdpi.com
Cryptococcus gattii species complex (CGSC) is a basidiomycete haploid yeast and globally
distributed mammalian pathogen. CGSC is comprised of six distinct lineages (VGI, VGII …
distributed mammalian pathogen. CGSC is comprised of six distinct lineages (VGI, VGII …
Roles for structural biology in the discovery of drugs and agrochemicals targeting sterol 14α-demethylases
Antifungal drugs and antifungal agrochemicals have significant limitations. These include
several unintended consequences of their use including the growing importance of intrinsic …
several unintended consequences of their use including the growing importance of intrinsic …