Macrophage polarization and plasticity in systemic lupus erythematosus
MM Ahamada, Y Jia, X Wu - Frontiers in immunology, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune disease that attacks almost every
organ. The condition mostly happens to adults but is also found in children, and the latter …
organ. The condition mostly happens to adults but is also found in children, and the latter …
Statin-regulated phagocytosis and efferocytosis in physiological and pathological conditions
Efferocytosis (clearance of apoptotic cells by phagocytosis without inducing inflammation
and autoimmunity) is an important mechanism in the resolution of inflammatory processes …
and autoimmunity) is an important mechanism in the resolution of inflammatory processes …
Apoptotic neurons and amyloid-beta clearance by phagocytosis in Alzheimer's disease: Pathological mechanisms and therapeutic outlooks
A Tajbakhsh, M Read, GE Barreto… - European Journal of …, 2021 - Elsevier
Neuronal survival and axonal renewal following central nervous system damage and in
neurodegenerative illnesses, such as Alzheimer's disease (AD), can be enhanced by fast …
neurodegenerative illnesses, such as Alzheimer's disease (AD), can be enhanced by fast …
[HTML][HTML] The complex roles of efferocytosis in cancer development, metastasis, and treatment
When tumor cells are killed by targeted therapy, radiotherapy, or chemotherapy, they trigger
their primary tumor by releasing pro-inflammatory cytokines. Microenvironmental …
their primary tumor by releasing pro-inflammatory cytokines. Microenvironmental …
Use of DAMPs and SAMPs as therapeutic targets or therapeutics: a note of caution
WG Land - Molecular Diagnosis & Therapy, 2020 - Springer
This opinion article discusses the increasing attention paid to the role of activating damage-
associated molecular patterns (DAMPs) in initiation of inflammatory diseases and …
associated molecular patterns (DAMPs) in initiation of inflammatory diseases and …
Alarmins and c-Jun N-Terminal Kinase (JNK) signaling in neuroinflammation
ND Anfinogenova, MT Quinn, IA Schepetkin… - Cells, 2020 - mdpi.com
Neuroinflammation is involved in the progression or secondary injury of multiple brain
conditions, including stroke and neurodegenerative diseases. Alarmins, also known as …
conditions, including stroke and neurodegenerative diseases. Alarmins, also known as …
Efferocytosis in multisystem diseases
Y Zhang, Y Wang, J Ding, P Liu - Molecular medicine …, 2022 - spandidos-publications.com
Efferocytosis, the phagocytosis of apoptotic cells performed by both specialized phagocytes
(such as macrophages) and non‑specialized phagocytes (such as epithelial cells), is …
(such as macrophages) and non‑specialized phagocytes (such as epithelial cells), is …
Macrophage efferocytosis in cardiac pathophysiology and repair
As an integral component of cardiac tissue, macrophages are critical for cardiac
development, adult heart homeostasis, as well as cardiac healing. One fundamental function …
development, adult heart homeostasis, as well as cardiac healing. One fundamental function …
The regulation of efferocytosis signaling pathways and adipose tissue homeostasis in physiological conditions and obesity: Current understanding and treatment …
Obesity is associated with changes in the resolution of acute inflammation that contribute to
the clinical complications. The exact mechanisms underlying unresolved inflammation in …
the clinical complications. The exact mechanisms underlying unresolved inflammation in …
The effect of cigarette smoke exposure on efferocytosis in chronic obstructive pulmonary disease; molecular mechanisms and treatment opportunities
Cigarette smoking-related inflammation, cellular stresses, and tissue destruction play a key
role in lung disease, such as chronic obstructive pulmonary disease (COPD). Notably …
role in lung disease, such as chronic obstructive pulmonary disease (COPD). Notably …