Worldwide, more than 7 million children have now been born after ART: these delivery rates
are steadily rising and now comprise 2–6% of births in the European countries. To achieve …

Objective To determine whether there are any increases in pregnancy-related complications
and adverse pregnancy outcomes in singleton pregnancies after assisted reproductive …

Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Background The extent to which birth defects after infertility treatment may be explained by
underlying parental factors is uncertain. Methods We linked a census of treatment with …

BACKGROUND Assisted reproduction technology (ART) is used worldwide, at increasing
rates, and data show that some adverse outcomes occur more frequently than following …

STUDY QUESTION What is the association between ART conception and treatment
parameters and the risk of birth defects? SUMMARY ANSWER Compared to naturally …

Importance Intracytoplasmic sperm injection (ICSI) is increasingly used in patients without
severe male factor infertility without clear evidence of a benefit over conventional in vitro …

BACKGROUND It has been 10 years since we carried out a systematic search of the
literature on birth defect risk in infants born following assisted reproductive technology (ART) …

Infertility, defined as the inability to conceive within 1 year of unprotected intercourse, affects
an estimated 80 million individuals worldwide, or 10-15% of couples of reproductive age …

Objective There is no consensus in current practice guidelines on whether conception by in-
vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) techniques is an indication for …