Despite a steady decline in fossil resources in past few decades, demand for petroleum-
based chemicals and polymers has increased sharply. As the dead end of the petroleum …

Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

The bio-based platform chemicals 2, 3-butanediol (BDO) and acetoin have various
applications in chemical, cosmetics, food, agriculture, and pharmaceutical industries …

Corynebacterium glutamicum, Escherichia coli, and Saccharomyces cerevisiae in particular,
have become established as important industrial workhorses in biotechnology. Recent years …

Efficient xylose utilization is one of the most important pre-requisites for developing an
economic microbial conversion process of terrestrial lignocellulosic biomass into biofuels …

Butanediol (2, 3-BD) has great potential for diverse industries, including chemical,
cosmetics, agriculture, and pharmaceutical areas. However, its industrial production and …

The main focus in development of yeast cell factories has generally been on establishing
optimal activity of heterologous pathways and further metabolic engineering of the host …

Numerous metabolic engineering strategies have allowed yeasts to efficiently assimilate
xylose, the second most abundant sugar component of lignocellulosic biomass. During the …

Background To develop pathways for advanced biofuel production, and to understand the
impact of host metabolism and environmental conditions on heterologous pathway …

The production of biofuels by recombinant Escherichia coli is restricted by the toxicity of the
products. 2, 3-Butanediol (2, 3-BD), a platform and fuel bio-chemical with low toxicity to …