Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles: challenges in clinical applications
Stem cell therapy has garnered much attention and application in the past decades for the
treatment of diseases and injuries. Mesenchymal stem cells (MSCs) are studied most …
treatment of diseases and injuries. Mesenchymal stem cells (MSCs) are studied most …
[HTML][HTML] Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology
S Liu, M Fan, JX Xu, LJ Yang, CC Qi, QR Xia… - Journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …
[HTML][HTML] Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Y Fan, Z Chen, M Zhang - Journal of Translational Medicine, 2022 - Springer
Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
[HTML][HTML] Adipose-derived stem cells secretome and its potential application in “stem cell-free therapy”
A Trzyna, A Banaś-Ząbczyk - Biomolecules, 2021 - mdpi.com
Adipose-derived stem cells (ASCs) secrete many cytokines, proteins, growth factors, and
extracellular vesicles with beneficial outcomes that can be used in regenerative medicine. It …
extracellular vesicles with beneficial outcomes that can be used in regenerative medicine. It …
[HTML][HTML] The functions and clinical application potential of exosomes derived from adipose mesenchymal stem cells: a comprehensive review
P Hong, H Yang, Y Wu, K Li, Z Tang - Stem cell research & therapy, 2019 - Springer
Exosomes are extracellular membranous nanovesicles that mediate local and systemic
intercellular communication by transporting proteins or nucleic acids (DNA and RNA) into …
intercellular communication by transporting proteins or nucleic acids (DNA and RNA) into …
Adipose‐Derived stem cells: current applications and future directions in the regeneration of multiple tissues
J Zhang, Y Liu, Y Chen, L Yuan, H Liu… - Stem Cells …, 2020 - Wiley Online Library
Adipose‐derived stem cells (ADSCs) can maintain self‐renewal and enhanced
multidifferentiation potential through the release of a variety of paracrine factors and …
multidifferentiation potential through the release of a variety of paracrine factors and …
Diagnostic and therapeutic potential of exosomes in Alzheimer's disease
T Soares Martins, D Trindade, M Vaz… - Journal of …, 2021 - Wiley Online Library
Exosomes are small extracellular vesicles released by almost all cell types in physiological
and pathological conditions. The exosomal potential to unravel disease mechanisms, or to …
and pathological conditions. The exosomal potential to unravel disease mechanisms, or to …
[HTML][HTML] Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine
D Lopes, J Lopes, M Pereira-Silva, D Peixoto… - Military Medical …, 2023 - Springer
A bio-inspired strategy has recently been developed for camouflaging nanocarriers with
biomembranes, such as natural cell membranes or subcellular structure-derived …
biomembranes, such as natural cell membranes or subcellular structure-derived …
[HTML][HTML] Mesenchymal stem cell-derived exosome: a promising alternative in the therapy of Alzheimer's disease
M Guo, Z Yin, F Chen, P Lei - Alzheimer's Research & Therapy, 2020 - Springer
Alzheimer's disease (AD) has been a devastating public health with the development of
global aging. Approaches for reducing the current AD epidemic are becoming a primary …
global aging. Approaches for reducing the current AD epidemic are becoming a primary …