Significance: Excessive and prolonged proinflammatory responses are associated with
oxidative stress, which is commonly observed during chronic tuberculosis (TB). Such …

Mycobacterium avium complex (MAC) is the main causative agent of infectious diseases in
humans among nontuberculous mycobacteria (NTM) that are ubiquitous organisms found in …

Moxifloxacin is central to treatment of multidrug-resistant tuberculosis. Effects of moxifloxacin
on the Mycobacterium tuberculosis redox state were explored to identify strategies for …

The mechanisms whereby Mycobacterium tuberculosis (Mtb) rewires the host metabolism in
vivo are surprisingly unexplored. Here, we used three high-resolution mass spectrometry …

Tuberculosis (TB) still causes significant morbidity and mortality worldwide, especially in
persons living with human immunodeficiency virus (HIV). This disease is hallmarked by …

Introduction Endoplasmic reticulum (ER) stress has emerged as a key player in insulin
resistance (IR) progression in skeletal muscle. Recent reports revealed that ER stress …

Abstract During infection, Mycobacterium tuberculosis (Mtb) rewires distinct host signaling
pathways, resulting in pathogen-favorable outcomes. Oxidative stress build-up is a key …

With tuberculosis, the emergence of fluoroquinolone resistance erodes the ability of
treatment to interrupt the progression of MDR-TB to XDR-TB. One way to reduce the …

Oxidative stress is a common feature of tuberculosis (TB), and persons with reduced
antioxidants are at more risk of TB. TB patients with relatively severe oxidative stress had …

Background: Extrapulmonary tuberculosis (EPTB) accounts for a fifth of all Mycobacterium
tuberculosis (M. tb) infections worldwide. The rise of multidrug resistance in M. tb alongside …